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Biophysics for therapeutic protein development

Autore: Linda O Narhi
Editore: New York : Springer, ©2013.
Serie: Biophysics for the life sciences.
Edizione/Formato:   eBook : Document : EnglishVedi tutte le edizioni e i formati
Banca dati:WorldCat
Sommario:
This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the  Per saperne di più…
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Genere/forma: Electronic books
Informazioni aggiuntive sul formato: Print version:
Narhi, Linda O.
Biophysics for Therapeutic Protein Development
Dordrecht : Springer, c2013
Tipo materiale: Document, Risorsa internet
Tipo documento: Internet Resource, Computer File
Tutti gli autori / Collaboratori: Linda O Narhi
ISBN: 9781461443162 1461443164
Numero OCLC: 828794658
Descrizione: 1 online resource (297 p.)
Contenuti: Introduction / Linda O. Narhi --
High-Throughput Biophysical Approaches to Therapeutic Protein Development / Feng He, Vladimir I. Razinkov --
Techniques for Higher-Order Structure Determination / James Kranz, Fatma AlAzzam, Atul Saluja --
Biophysical Techniques for Protein Size Distribution Analysis / Ziping Wei, Alla Polozova --
Qualification of Biophysical Methods for the Analysis of Protein Therapeutics / Yijia Jiang, Cynthia Li, John Gabrielson --
Application of Biophysics to the Early Developability Assessment of Therapeutic Candidates and Its Application to Enhance Developability Properties / Hasige Sathish, Nicolas Angell, David Lowe --
Application of Biophysics in Formulation, Process, and Product Characterization: Selected Case Studies / Satish K. Singh, Qin Zou, Min Huang --
Biophysical Analysis in Support of Development of Protein Pharmaceuticals / Sreedhara Alavattam, Barthelemy Demeule --
Case Studies Applying Biophysical Techniques to Better Characterize Protein Aggregates and Particulates of Varying Size / Tingting Wang, Sangeeta B. Joshi --
Investigation of Nonconformance During Protein Therapeutic Manufacturing / Zai-Qing Wen, Gianni Torraca, Guiyang Li --
Higher-Order Structure and Protein Aggregate Characterization of Protein Therapeutics: Perspectives from Good Manufacturing Practices and Regulatory Guidance / Evi B. Struble, John F. Cipollo.
Titolo della serie: Biophysics for the life sciences.
Responsabilità: Linda O. Narhi, editor.
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Abstract:

This book assesses techniques used in therapeutic development across the product lifecycle from early discovery through expression and purification, large scale production, formulation development,  Per saperne di più…

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