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Biothermodynamics. Part C

Author: Michael L Johnson; Jo M Holt; Gary K Ackers
Publisher: Amsterdam [Netherlands] ; Boston [Mass.] : Elsevier/Academic Press, 2011.
Series: Methods in enzymology, v. 488.
Edition/Format:   eBook : Document : English : 1st edView all editions and formats
Database:WorldCat
Summary:
The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. Elucidates the relationships between  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Biothermodynamics. Part C.
Amsterdam [Netherlands] ; Boston [Mass.]: Elsevier/Academic Press, 2011
(OCoLC)697863301
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Michael L Johnson; Jo M Holt; Gary K Ackers
ISBN: 9780123812681 0123812682
OCLC Number: 700703957
Description: 1 online resource (xlv, 354 pages, [8] pages of plates) : illustrations (some color).
Contents: 1. Measurement and analysis of equilibrium binding titrations : a beginner's guide / Dorothy Beckett --
2. Macromolecular competition titration method : accessing thermodynamics of the unmodified macromolecule-ligand interactions through spectroscopic titrations of fluorescent analogs / Wlodzimierz Bujalowksi and Maria J. Jezewska --
3. Analysis of PKR-RNA interactions by sedimentation velocity / C. Jason Wong, Katherine Launer-Felty, and James L. Cole --
4. Structural and thermodynamic analysis of PDZ-ligand interactions / Tyson R. Shepherd and Ernesto J. Fuentes --
5. Thermodynamic analysis of metal ion-induced protein assembly / Andrew B. Herr and Deborah G. Conrady --
6. Thermodynamic dissection of colicin interactions / Nicholas G. Housden and Colin Kleanthous --
7. Energetics of Src homology domain interactions in receptor tyrosine kinase-mediated signaling / John E. Ladbury and Stefan T. Arold --
8. Structural and functional energetic linkages in allosteric regulation of muscle pyruvate kinase / J. Ching Lee and Petr Herman --
9. Analysis of free energy versus temperature curves in protein folding and macromolecular interactions / Vince J. LiCata and Chin-Chi Liu --
10. Application of the sequential n-step kinetic mechanism to polypeptide translocases / Aaron L. Lucius, Justin M. Miller, and Burki Rajendar --
11. A coupled equilibrium approach to study nucleosome thermodynamics / Andrew J. Andrews and Karolin Luger --
12. Quantitative methods for measuring DNA flexibility in vitro and in vivo / Justin P. Peters, Nicole A. Becker, Emily M. Rueter, Zeljko Bajzer, Jason D. Kahn, and L. James Maher III.
Series Title: Methods in enzymology, v. 488.
Responsibility: edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers.

Abstract:

Presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. This title elucidates the relationships between  Read more...

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