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The blood-brain barrier and drug delivery to the CNS

Author: D J Begley; M W B Bradbury; Jörg Kreuter
Publisher: New York : Dekker, ©2000.
Edition/Format:   eBook : Document : Conference publication : EnglishView all editions and formats
Summary:

Addresses how to determine drug permeability across the blood-brain barrier. This book covers the research on the blood-brain barrier, the problems of and solutions to drug delivery to the central  Read more...

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Genre/Form: Electronic books
Congresses
Additional Physical Format: Print version:
Blood-brain barrier and drug delivery to the CNS.
New York : Dekker, ©2000
(DLC) 00024059
Material Type: Conference publication, Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: D J Begley; M W B Bradbury; Jörg Kreuter
ISBN: 0585393532 9780585393537 0824703944 9780824703943 0824741994 9780824741990
OCLC Number: 49851555
Description: 1 online resource (x, 248 pages) : illustrations
Contents: History and Physiology of the Blood-Brain Barrier in Relation to Delivery of Drugs to the BrainMichael W. BradburyPhysicochemical Factors that Influence Brain UptakeMichael H. Abraham and James A. PlattsThe Development of In Vitro Models for the Blood-Brain and Blood-CSF BarriersChristiane Engelbertz, Dorothea Korte, Thorsten Nitz, Helmut Franke, Matthias Haselbach, Joachim Wegener, and Hans-Joachim GallaIn Vitro Models of the Blood-Brain Barrier and Their Use in Drug DevelopmentR. Cecchelli, B. Dehouck, L. Descamps, L. Fenart, V. Buee-Scherrer, C. Duhem, G. Torpier, and M. P. DehouckThe Application of Microdialysis Techniques to the Study of Drug Transport Across the Blood-Brain BarrierA. G. de Boer, Elizabeth C. M. de Lange, Inez C. J. van der Sandt, and Douwe D. BreimerThe Role of Brain Extracellular Fluid Production and Efflux Mechanisms in Drug Transport to the BrainDavid J. Begley, Anthony Regina, Francoise Roux, Ehsan Ullah Khan, Christopher Rollinson, and Joan AbbottThe Relevance of P-Glycoprotein in Drug Transport to the Brain: The Use of Knockout Mice as a Model SystemUlrich MayerSpecific Mechanisms for Transporting Drugs Into BrainAkira TsujiDrug Metabolism in the Brain: Benefits and RisksAlain Minn, Ramon D. S. El-Bacha, Claire Bayol-Denizot, Philippe Lagrange, Funmilayo G. Suleman, and Daniela GradinaruTargeting Macromolecules to the Central Nervous SystemUlrich BickelUsing Nanoparticles to Target Drugs to the Central Nervous SystemJoerg Kreuter and Renad N. AlyautdinBasic CNS Drug Transport and Binding Kinetics In VivoAlbert Gjedde, Antony D. Gee, and Donald Frederick Smith
Responsibility: edited by David J. Begley, Michael W. Bradbury, Jörg Kreuter.

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..".a compact monograph that brings readers up to date on the blood-brain barrier and how scientists determine drug/chemical permeability across this functional partition....The contributions are a Read more...

 
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