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| Genre/Form: | Electronic books |
|---|---|
| Material Type: | Document, Internet resource |
| Document Type: | Internet Resource, Computer File |
| All Authors / Contributors: |
Elizabeth Shane |
| ISBN: | 9786611005160 6611005161 0080490549 9780080490540 |
| OCLC Number: | 441784707 |
| Description: | 1 online resource (xxi, 494 p.) : ill. |
| Contents: | Cover -- Copyright Page -- Contents -- Preface -- Contributors -- Part I: Basic Transplantation and Bone Biology -- Chapter 1. Principles of Transplantation Immunology -- I. Immunological Mechanisms -- II. Immunosuppressants -- III. Rejection Management -- References -- Chapter 2. Bone Biology: Bone Structure and Remodeling -- I. Introduction -- II. Bone Structure -- III. Bone Remodeling -- IV. Systemic Regulators of Bone Growth and Remodeling -- V. Local Regulators of Bone Remodeling -- VI. Conclusion -- References -- Chapter 3. Skeletal Effects of Glucocorticoids: Basic and Clinical Aspects -- I. Introduction -- II. Mechanisms of Glucocorticoid Action in Bone -- III. Clinical Aspects of Glucocorticoid-Induced Osteoporosis -- IV. Management of Glucocorticoid-Induced Osteoporosis -- References -- Chapter 4. Transplantation Bone Disease Induced by Non-Steroid Immunosuppressants -- I. Introduction -- II. Calcineurin Inhibitors -- III. Mechanisms -- IV. Therapeutic Considerations -- V. Clinical Studies Supporting the Role of Calcineurin Inhibitors in Bone Loss after Transplantation -- VI. Other Immune-Modifying Drugs -- VII. Cancer Therapies and Hypogonadism -- VIII. Conclusion -- References -- Chapter 5. Molecular Effects of Calcineurin Inhibitors -- I. Introduction -- II. Cyclosporin A -- III. FK506 -- IV. Mechanism of Bone Loss with Calcineurin Inhibition -- V. Rapamycin -- VI. Summary -- References -- Chapter 6. Bone and the Immune System -- I. Introduction -- II. Cells and Cytokines That Regulate Osteoclast Formation -- III. Mechanism of Action of Estrogen in Bone -- IV. T Cell-Produced Cytokines and Bone Loss -- V. Mechanisms of Estrogen Regulation of T-cell Production of TNF -- VI. Estrogen Regulation of IFN? Production and in Vivo Effects of IFN? in Bone -- VII. The Role of IL-7 in PTBD and Postmenopausal Bone Loss -- VIII. Conclusions -- References -- Part II: Pathogenesis of Transplantation-Related Bone Disease -- Chapter 7. Fracture Prevalence and Incidence in Solid Organ Transplant Recipients -- I. Introduction -- II. Liver Transplantation -- III. Cardiac Transplantation -- IV. Lung Transplantation -- V. Kidney Transplantation -- VI. Kidney-Pancreas Transplantation -- VII. Summary and Conclusions -- References -- Chapter 8. Bone Histomorphometry and Its Application to Transplantation Bone Disease -- I. Introduction -- II. Pathophysiology of Bone Loss after Transplantation -- III. Histomorphometric Assessment of Bone Remodelling and Structure -- IV. Bone Histomorphometric Analysis of Transplantation Bone Disease -- References -- Chapter 9. The Role of Parathyroid Hormone in the Evolution of Bone Loss after Organ Transplantation -- I. Introduction -- II. Isolated Glucocorticoid Use and PTH -- III. Isolated Calcineurin Inhibitor Use and PTH -- IV. Transplant-Induced Osteoporosis and PTH: Dynamic Evidence -- V. Transplant-Induced Osteoporosis and PTH: Densitometric Evidence -- VI. Transplant-Induced Osteoporosis and PTH: Histo. |
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