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Bone Morphogenetic Proteins : From Local to Systemic Therapeutics

Author: Slobodan Vukicevic; Kuber T Sampath
Publisher: Basel ; Boston : Birkhäuser, ©2008.
Series: PIR (Series)
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Bone morphogenetic proteins.
Basel ; Boston : Birkhäuser, ©2008
(DLC) 2008921606
(OCoLC)166383594
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Slobodan Vukicevic; Kuber T Sampath
ISBN: 9783764385521 3764385529 9783764385514 3764385510
OCLC Number: 288473605
Description: 1 online resource (xi, 343 pages) : illustrations (some color).
Contents: Development of a novel compression-resistant carrier for recombinant human bone morphogenetic protein-2 (rhBMP-2) and preliminary clinical results --
Use of recombinant human BMP-2 in orthopedic trauma --
The application of recombinant human bone morphogenetic protein on absorbable collagen sponge (rhBMP-2/ACS) to reconstruction of maxillofacial bone defects --
Clinical outcomes using rhBMP-2 in spinal fusion applications --
Bone morphogenetic protein signaling is fine-tuned on multiple levels --
Dissection of bone morphogenetic protein signaling using genome-engineering tools --
Alterations of BMP signaling pathway(s) in skeletal diseases --
Signaling cross-talk by bone morphogenetic proteins --
The role and mechanisms of bone morphogenetic protein 4 and 2 (BMP-4 and BMP-2) in postnatal skeletal development --
The role of bone morphogenetic protein 4 (BMP-4) in tooth development --
Bone morphogenetic protein antagonists and kidney --
Induction of cementogenesis and periodontal ligament regeneration by the bone morphogenetic proteins --
Control of bone mass by sclerostin: Inhibiting BMP- and WNT-induced bone formation --
Bone morphogenetic proteins in cartilage biology --
Systemic administration of bone morphogenetic proteins.
Series Title: PIR (Series)
Responsibility: Slobodan Vukicevic, Kuber T. Sampath, editors.

Abstract:

Completing the PIR series, this volume summarizes the major advances made in the local and systemic use of bone morphogenetic proteins (BMPs). biological actions of BMPs in bone, cartilage, and  Read more...

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