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Brain ischemia

Author: E I Gusev; Veronica I Skvortsova
Publisher: New York : Kluwer Academic/Plenum Publishers, ©2003.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Ischemia is localized tissue anemia due to obstruction of the inflow of arterial blood, thus brain ischemia is the condition where insufficient blood is delivered to the brain.

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: E I Gusev; Veronica I Skvortsova
ISBN: 0306476940 9780306476945
OCLC Number: 51095923
Description: xiv, 382 pages : illustrations ; 24 cm
Contents: Mechanisms of ischemic brain damage --
Hemodynamic events associated with acute focal brain ischemia and reperfusion. Ischemic penumbra --
Cellular reactions in response to acute focal brain ischemia --
Energy failure induced by brain ischemia --
Glutamate-calcium cascade --
Metabolic acidosis and ischemic damage --
Delayed neuronal death following acute focal brain ischemia --
Gene expression and subsequent molecular events in response to acute brain ischemia --
Microglial activation, cytokine production, and local inflammation in focal brain ischemia --
Autoimmune mechanisms of trophic dysfunction and ischemic brain damage --
Programmed cell death. Apoptosis in focal brain ischemia --
Reaction of the stress-mediating endocrine system in response to acute brain ischemia --
Molecular mechanisms of post-ischemic reparation events --
Neuroprotection in brain ischemia --
Modern therapeutic approaches to acute focal brain ischemia. Basic strategies for neuroprotection --
Primary neuroprotection --
Secondary neuroprotection --
Reparative therapy --
Strategies and prospects for development of neuroprotective therapy for brain ischemia --
Conclusion.
Responsibility: Eugene Gusev and Veronica I. Skvortsova.
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