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Cancer chemotherapy and biotherapy : principles and practice

Author: Bruce Chabner; Dan L Longo
Publisher: Philadelphia : Wolters Kluwer Health/Lippincott Williams & Wilkins, ©2011.
Edition/Format:   Print book : English : 5th edView all editions and formats
Summary:
"Updated to include the newest drugs and those currently in development, Cancer Chemotherapy and Biotherapy, Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents--their mechanisms of action, interactions with other agents, toxicities, side effects, and  Read more...
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Bruce Chabner; Dan L Longo
ISBN: 9781605474311 1605474312
OCLC Number: 640072409
Description: xv, 812 pages : illustrations (some color) ; 29 cm
Contents: Clinical strategies for cancer treatment: the role of drugs --
Target identification and drug discovery --
Clinical drug development and marketing approval --
Principles of pharmacokinetics --
Delivering anticancer drugs to brain tumors --
Pharmacogenetics --
Physical barriers to drug delivery --
Antifolates --
5-fluoropyrimidines --
Cytidine analogues --
Purine antimetabolites --
Hydroxyurea --
Antimitotic drugs --
Alkylating agents --
Platinum analogues --
Bleomycin and other antitumor antibiotics --
Topoisomerase I-targeting drugs --
Topoisomerase II inhibitors: anthracyclines --
Topoisomerase II inhibitors: the epipodophyllotoxins --
Asparaginase --
Proteasome inhibitors --
Histone deacetylase inhibitors in oncology --
Differentiating agents --
Arsenic trioxide --
Antibodies --
Inhibitors of tumor angiogenesis --
Epidermal growth factor receptor inhibitors --
HER2 inhibitors --
Molecular targeted drugs --
Signaling inhibitors: IGFR, PI3K pathway, embryonic signaling inhibitors, and mitotic kinase inhibitors --
Cytokine therapy for cancer --
Cancer vaccines --
Adoptive cellular therapies --
Thalidomide and its analogs in the treatment of hematologic malignancies, including multiple myeloma, and solid tumors --
Hormonal therapy of breast cancer --
Hormone therapy for prostate cancer --
Drug therapy of pain in cancer patients --
Hematopoietic growth factors --
Antinausea medications --
Bisphosphonates and other bone-targeted therapies --
Intravenous access and catheter management --
Late effects of cancer chemotherapy --
Infertility after cancer chemotherapy.
Responsibility: [edited by] Bruce A. Chabner, Dan L. Longo.

Abstract:

A comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, it provides information on various drugs and biological agents - their mechanisms  Read more...

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