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Cancer targeted drug delivery : an elusive dream

Autor: You Han Bae; Randall J Mrsny; Kinam Park
Editora: New York : Springer, 2013.
Edição/Formato   e-book : Documento : InglêsVer todas as edições e formatos
Base de Dados:WorldCat
Resumo:
This book was conceived from a simple question as to why cancer is so difficult to treat. Ultimately we want to find ways to cure cancers, but that may be an elusive dream at least with the technologies we have now and expect to have in the near future. This leads the question of whether it is possible to improve current cancer treatment methods, especially from the perspective of enhancing targeted drug delivery to  Ler mais...
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Gênero/Forma: Electronic books
Formato Físico Adicional: Print version:
Cancer targeted drug delivery
(OCoLC)841495292
Tipo de Material: Documento, Recurso Internet
Tipo de Documento: Recurso Internet, Arquivo de Computador
Todos os Autores / Contribuintes: You Han Bae; Randall J Mrsny; Kinam Park
ISBN: 9781461478768 1461478766 1461478758 9781461478751
Número OCLC: 857714017
Notas: Includes index.
Descrição: 1 online resource.
Conteúdos: Part I: History of Cancer Targeting Efforts. A Time Travel Journey Through Cancer Therapies / Ana S. Cravo, Randall J. Mrsny --
Nanotechnology for Cancer Treatment: Possibilities and Limitations / Joseph W. Nichols, You Han Bae --
Part II: Targeting Issues. Vascular Targeting Approaches to Treat Cancer / Joseph W. Wragg, Roy Bicknell --
Tumor Immunotherapy by Utilizing a Double-Edged Sword, Chemokines / Naofumi Mukaida, So-ichiro Sasaki, Tomohisa Baba --
Part III: General Tumor Physiology and Microenvironment Issues. Cancer Biology: Some Causes for a Variety of Different Diseases / Abood Okal, Shams Reaz, Carol S. Lim --
Cancer Stromal Targeting (CAST) Therapy and Tailored Antibody Drug Conjugate Therapy Depending on the Nature of Tumor Stroma / Yasuhiro Matsumura., Masahiro Yasunaga, Shino Manabe --
Cancer Cell Respiration: Hypoxia and pH in Solid Tumors / Dong Yun Lee, Taiyoun Rhim, Minhyung Lee --
Tumor Vasculature, EPR Effect, and Anticancer Nanomedicine: Connecting the Dots / Sebastien Taurin ... et al. --
Pressure Gradients in Solid Tumors / Shawn Stapleton, Michael F. Milosevic --
The ADAMs: New Therapeutic Targets for Cancer? / M.J. Duffy ... et al. --
Role of the Extracellular Matrix: Enzyme Activities and Metastasis / Il-Kyu Choi, Chae-Ok Yun --
The Role of Non-cancerous Cells in Cancer: Pancreatic Ductal Adenocarcinoma as a Model to Understand the Impact of Tumor Microenvironment on Epithelial Carcinogenesis / Mert Erkan, Tania Brocks, Helmut Friess --
Part IV: The Dynamic Problem of Tumor Heterogeneity. Heterogeneity of Cancers and Its Implication for Targeted Drug Delivery / Tracy A. Denison, You Han Bae. --
A Study of Cancer Heterogeneity: From Genetic Instability to Epigenetic Diversity in Colorectal Cancer / Maria Giovanna Francipane., Eric Lagasse --
Nanotherapeutics in Multidrug Resistance / Min Han, Jian-Qing Gao. --
Stem Cells and Cancer / Dejuan Kong ... et al. --
Mechanisms of Metastasis / Ngoc-Han Ha, Farhoud Faraji, Kent W. Hunter --
Part V: Reaching Cancer Cells. Cancer-Specific Ligand-Receptor Interactions / Ewelina Kluza ... et al. --
Targeting Drugs to Cancer: A Tough Journey to the Tumor Cell / Shiran Ferber, Galia Tiram, Ronit Satchi-Fainaro --
Long Circulation and Tumor Accumulation / Sandra N. Ekdawi ... et al. --
Convective and Diffusive Transport in Drug Delivery / Abraham R. Tzafriri, Elazer R. Edelman --
Intravital Real-Time Confocal Laser Scanning Microscopy for the In Situ Evaluation of Nanocarriers / Yu Matsumoto ... et al. --
The EPR Effect in Cancer Therapy / Ji Young Yhee ... et al. --
Part VI: Preclinical Modeling. In Vitro Three-Dimensional Cancer Culture Models / Waseem Asghar ... et al. --
Complex Transport Around Tumor: Need for Realistic In Vitro Tumor Transport Model / Bumsoo Han --
Part VII: Prospective and Future Direction. The Missing Components Today and the New Treatments Tomorrow / Kinam Park, You Han Bae, Randall J. Mrsny.
Responsabilidade: You Han Bae, Randall J. Mrsny, Kinam Park, editors.
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Resumo:

This volume provides information related to the difficulties in treating cancers through targeted drug delivery. It examines our current understanding of cancer biology as well as potential  Ler mais...

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