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Captopril and Hypertension

Author: David B Case; Edmund H Sonnenblick; John H Laragh
Publisher: Boston, MA : Springer US, 1980.
Series: Topics in Cardiovascular Disease.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This monograph was developed from a collection of papers that were origi nally presented at a symposium entitled "Pathogenesis of Hypertension" held at the Henry Chauncy Conference Center, Princeton. New Jersey. These manuscripts were subsequently revised, updated, and reorganized in a manner suitable for this publication. The symposium was planned to stimu late interest among investigators and clinicians alike in  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: David B Case; Edmund H Sonnenblick; John H Laragh
ISBN: 9781461591795 1461591791
OCLC Number: 851800468
Description: 1 online resource (volumes).
Contents: I Humoral and Physiological Mechanisms in Hypertension --
1Blood Pressure Homeostasis --
2Mechanisms of Hypertension Induced by Electrolyte-Active Steroids --
3The Relationship of the Renal Medulla to the Hypertensive State --
4The Influence of Various Neurological Defects on the Release of Renin in Normal Man --
5Angiotensin as a Determinant of Renal Perfusion and Function --
6Systemic Vascular Resistance: Regulation and Effect on Left Ventricular Function --
II Angiotensin-Converting Enzyme: Its Role and Development of Inhibitors --
7Physiological, Biochemical, and Immunologic Aspects of Angiotensin-Converting Enzyme --
8Design of New Antihypertensive Drugs: Potent and Specific Inhibitors of Angiotensin-Converting Enzyme --
9Captopril (Capoten®; SQ 14,225) (D-3-Mercapto-2-methylpropanoyl-L-proline): A Novel Orally Active Inhibitor of Angiotensin-Converting Enzyme and Antihypertensive Agent --
10Toxicologic and Drug Metabolic Studies of SQ 14,225 in Animals --
11Captopril: An Oral Angiotensin-Converting Enzyme Inhibitor Active in Man --
III Clinical Use of Converting Enzyme Inhibitors --
12The Renin System in High Blood Pressure, from Disbelief to Reality: Converting Enzyme Blockade for Analysis and Treatment --
13Experiences with Blockade of the Renin System in Human Hypertension Using Converting Enzyme Inhibitor SQ 20,881 and Saralasin --
14The Use of SQ 20,881 Converting Enzyme Inhibitor (Teprotide) for Diagnostic Purposes in Hypertension --
15Clinical Experience with Blockade of the Renin-Angiotensin-Aldosterone System by an Oral Converting Enzyme Inhibitor (SQ 14,225, Captopril) in Hypertensive Patients.
Series Title: Topics in Cardiovascular Disease.
Responsibility: edited by David B. Case, Edmund H. Sonnenblick, John H. Laragh.

Abstract:

The symposium was planned to stimu- late interest among investigators and clinicians alike in the potential for a new class of drugs called converting enzyme inhibitors in clinical medicine.  Read more...

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