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Cardiac bioelectric therapy : mechanisms and practical implications

Author: Igor R Efimov; Mark W Kroll; Patrick J Tchou
Publisher: New York ; London : Springer, 2008.
Edition/Format:   Book : EnglishView all editions and formats
Database:WorldCat
Summary:
Pacing and defibrillation have become the leading therapeutic treatments of heart rhythm disorders, including bradycardia and tachycardia. The success of these therapies is largely due to centuries of scientific inquiry into the fundamental mechanisms of bioelectric phenomena in the heart. History of successful development of bioelectric therapies includes development of experimental and theoretical methodologies,  Read more...
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Document Type: Book
All Authors / Contributors: Igor R Efimov; Mark W Kroll; Patrick J Tchou
ISBN: 9780387794020 0387794026
OCLC Number: 233788057
Description: xxiii, 634 p. : ill. ; 26 cm.
Contents: History.- History of Cardiac Pacing.- History of Defibrillation.- Ventricular Fibrillation: A Historical Perspective.- Theory of Electric Stimulation and Defibrillation.- The Bidomain Theory of Pacing.- Bidomain Model of Defibrillation.- The Generalized Activating Function.- Theory of Electroporation.- Electrode Mapping of Defibrillation.- Critical Points and the Upper Limit of Vulnerability for Defibrillation.- The Role of Shock-Induced Nonregenerative Depolarizations in Ventricular Fibrillation and Defibrillation: The Graded Response Hypothesis.- Optical Mapping of Stimulation and Defibrillation.- Mechanisms of Isolated Cell Stimulation.- The Role of Microscopic Tissue Structure in Defibrillation.- Virtual Electrode Theory of Pacing.- The Virtual Electrode Hypothesis of Defibrillation.- Simultaneous Optical and Electrical Recordings.- Optical Mapping of Multisite Ventricular Fibrillation Synchronization.- Methodology.- The Bidomain Model of Cardiac Tissue: From Microscale to Macroscale.- Multielectrode Mapping of the Heart.- The Role of Electroporation.- Implications for Implantable Devices.- Lessons for the Clinical Implant.- Resonance and Feedback Strategies for Low-Voltage Defibrillation.- Pacing Control of Local Cardiac Dynamics.- Advanced Methods for Assessing the Stability and Control of Alternans.- The Future of the Implantable Defibrillator.- Lessons Learned from Implantable Cardioverter-Defibrillators Recordings.
Responsibility: edited by Igor R. Efimov, Mark W. Kroll, Patrick J. Tchou.
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This book presents a thematic collection of reviews written by the leading scientists working in bioengineering research laboratories, who have contributed to our understanding of the development of  Read more...

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From the reviews: "This book discusses the background of the theory and methodology that drive current pacing and defibrillation strategies. ... The most likely readers are electrophysiologists, Read more...

 
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