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Cardiotoxicity of non-cardiovascular drugs

Author: Giorgio Minotti
Publisher: Chichester, West Sussex, U.K. : Wiley, 2010.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"First book to deal with this important area of adverse drug reactions -- cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals. Covers four important therapeutic classes: psychoactive drugs; anticancer drugs; non-steroidal anti-inflammatory drugs; and anti-retroviral drugs. - Emphasis on the preclinical screening of  Read more...
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Document Type: Book
All Authors / Contributors: Giorgio Minotti
ISBN: 9780470772744 0470772743
OCLC Number: 495598837
Description: xvi, 342 pages : illustrations (some color) ; 24 cm
Contents: 1. Mitochondrial Dysfunction In Cell Injury and Cardiotoxicity --
Fabio Di Lisa, Martina Semenzato, Andrea Carpi, Sara Menazza, Nina Kaludercic, Roberta Menabò, Marcella Canton --
2. Cardiovascular Liabilities of Drugs: Regulatory Aspects --
Claudio Arrigoni --
3. Cellular Mechanisms, Molecular Targets, and Structure-Function Relationships In Drug-Induced Arrhythmias: The Case Of Antihistamines, Psychoactive Drugs, and Antimicrobial Agents --
Maria Virginia Soldovieri and Maurizio Taglialatela --
4. Cardiovascular Toxicity of Antitumor Drugs: Dimensions of the Problem in Children --
Rebecca Scully, Louis Pruitt, Steven E. Lipshultz --
5. Cardiovascular Toxicity of Antitumor Drugs: Dimension of the Problem in Adult Settings --
Joseph R. Carver and Chaitali J. Desai --
6. Diagnostic Aspects of Cardiovascular Toxicity of Antitumor Drugs --
Michael S. Ewer, Thomas M. Suter --
7. Cardiovascular Toxicity of Antitumor Drugs: Translating Molecular Mechanisms into Clinical Facts --
Pierantonio Menna, Emanuela Salvatorelli, Carlo Salsano, Luca Gianni*, and Giorgio Minotti --
8. NSAID Action and the Foundations for Cardiovascular Toxicity --
Anna L. Blobaum and Lawrence J. Marnett --
9. Cardiovascular toxicities of NSAIDS: Epidemiologic aspects --
Antonio González-Pe;rez, Luis Alberto Garci;a Rodriguez --
10. Cardiovascular Toxicities of Life-Saving Drugs: Antiviral Therapy --
James J. Kohler & William Lewis.
Responsibility: editor, Giorgio Minotti.

Abstract:

In Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of cardiac events induced by a broad variety of noncardiovascular drugs.  Read more...

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