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Cardiovascular Pharmacogenetics

Author: Martin R Wilkins
Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2004.
Series: Handbook of experimental pharmacology, 160.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This volume intends to provide a panorama of our current understanding of the role of genetic information in the management of cardiovascular disease. A recurring plea from the contributors is the need for more hypothesis-driven, rigorously conducted and analysed clinical research. Perhaps this compilation of knowledge will provide a springboard for the design of informative clinical studies.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Martin R Wilkins
ISBN: 9783662062142 3662062143
OCLC Number: 851372760
Description: 1 online resource (x, 407 pages).
Contents: Preface --
The Role of Genotyping in Pharmacological Therapy --
Pharmacogenetics and the Treatment of Cardiovascular Disease --
Genetic Polymorphisms and Cardiovascular Drug Metabolism --
Genes that Modify Susceptibility to Atherosclerosis: Targets for Drug Action --
Lipid Lowering Responses Modified by Genetic Variation --
The Genetic Basis of Essential Hypertension and its Implications for Treatment --
Genetic Predisposition to Cardiac Hypertrophy --
Genetic Determinants of Susceptibility, Prognosis and Treatment in Heart Failure --
The Genetics of Cardiac Channelopathies: Implications for Therapeutics --
Insulin Resistance and Cardiovascular Disease --
New Insights From Genetics --
Genetic Disruption of Nitric Oxide Synthases and Cardiovascular Disease --
Lessons from a Candidate Gene --
Association of Thrombotic Disease with Genetic Polymorphism of Haemostatic Genes --
Relevance to Pharmacogenetics --
Genetic Polymorphisms of Adhesion Molecules --
Genetic Regulation of Metalloproteinase Activity: Pathogenic and Therapeutic Implications --
Current Perspectives on Gene and Cell-based Therapies for Myocardial Protection, Rescue and Repair.
Series Title: Handbook of experimental pharmacology, 160.
Other Titles: With contributions by numerous experts
Responsibility: edited by Martin R. Wilkins.

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