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Cell Biology and Pathology of Myelin : Evolving Biological Concepts and Therapeutic Approaches

Author: Bernhard H J JuurlinkRichard M DevonJ Ronald DoucetteAdil J NazaraliDavid J SchreyerAll authors
Publisher: Boston, MA : Springer US : Imprint : Springer, 1997.
Series: Altschul symposia series, 4.
Edition/Format:   eBook : Document : EnglishView all editions and formats
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Fedoroff, Sergey.
Cell Biology and Pathology of Myelin : Evolving Biological Concepts and Therapeutic Approaches.
Boston : Springer US, ©1997
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Bernhard H J Juurlink; Richard M Devon; J Ronald Doucette; Adil J Nazarali; David J Schreyer; Valerie M K Verge
ISBN: 9781461559498 1461559499
OCLC Number: 840285994
Description: 1 online resource.
Contents: Myelin as a Dynamic Structure --
1. Structure and Function of Myelin, an Extended and Biochemically Modified Cell Surface Membrane --
2. Myelin Basic Protein, the “Executive” Molecule of the Myelin Membrane --
3. Myelin-Associated Glycoprotein: Ligand and/or Receptor --
4. Myelin/Oligodendrocyte Glycoprotein: A Molecular Analysis --
5. Molecular Biology of Hereditary Motor and Sensory Neuropathies --
6. Mutations of the Proteolipid Protein Gene: A Molecular Mechanism of CNS Dysmyelination --
7. Myelin Proteins as Mediators of Signal Transduction --
8. CNP in Myelination: Overexpression Alters Oligodendrocyte Morphogenesis --
9. The Role of the Gap Junction Protein Connexin32 in the Myelin Sheath --
10. The Role of Myelin Po Protein --
Factors Controlling the Expression of the Myelinating Phenotype --
11. Posttranscriptional Regulation of Myelin Basic Protein Gene Expression --
12. Molecular Control of Myelin Basic Protein Gene Expression --
13. Role of cAMP during the Process of Demyelination and Remyelination in Peripheral Nerve --
14. Characterization of an Axonal Protein Involved in Myelination --
15. Do Secretory Pathway SNARE Proteins Mediate Myelinogenesis? --
16. Expression of the PLP Gene and a PLP-LacZ Transgene in Oligodendrocytes --
17. Developmental Regulation of Schwann Cell Precursors and Schwann Cell Generation --
18. Protein Kinase C Regulates Process Formation by Oligodendrocytes --
19. Mechanism of Adhesion-Induced Regeneration/Differentiation of Oligodendrocytes --
20. A Procedure for Isolating Schwann Cells Developed for Analysis of the Mouse Embryonic Lethal Mutation NF1 --
21. Expansion of Oligodendrocyte Progenitors for Myelin Repair --
22. Generation of Oligodendrocyte Precursors from Human Neural Cells in Vitro --
Promoting Functional Recovery in White Matter --
23. Recent Insights into the Cellular Biology of Remyelination: Implications for Multiple Sclerosis --
24. Characterising the Adult Human Oligodendrocyte Progenitor --
25. The Repair of Central Nervous System Myelin: Cell Biology and Pharmacologic Action of Remyelination-Promoting Autoantibodies --
26. Inhibition of Human and Rat Glial Cell Function by Anti-Inflammatory Cytokines, Antioxidants, and Elevators of cAMP --
27. Oligodendrocytes and Axonal Regrowth: A Double-Edged Sword --
28. Functional Repair of Myelinated Fibers in the Spinal Cord by Transplantation of Glial Cells --
29. Axonal Regeneration in the Fish and Amphibian CNS: Myelin-Associated Neurite Growth Inhibitors and Adaptive Plasticity of Glial Cells --
30. Role of MAG as an Axon Growth Inhibitory Protein for Regeneration of Injured Neurons in the CNS --
31. Schwann Cells as Facilitators of Axonal Regeneration in CNS Fiber Tracts --
32. Olfactory Ensheathing Cells Can Be Induced to Express a Myelinating Phenotype --
33. Overcoming Myelin-Associated Inhibition of Axonal Regeneration after CNS Injury --
Abstract --
Contributors.
Series Title: Altschul symposia series, 4.
Other Titles: Proceedings of the Fourth International Altschul Symposium held at Saskatoon, Saskatchewan, Canada, June 27-29, 1996
Responsibility: edited by Bernhard H.J. Juurlink, Richard M. Devon, J. Ronald Doucette, Adil J. Nazarali, David J. Schreyer, Valerie M.K. Verge.

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