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Cellular Aspects of Hypertension

Author: Giacomo Bruschi; Alberico Borghetti
Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 1991.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
This book highlights an area where cardiovascular pharmacol- ogy and hypertension research are expected to advance in the near future. It shows how molecular concepts (such as recep- tor occupancy, transmembrane signalling and intracellular messengers) can be translated into effective therapy to the benefit of all patients.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Giacomo Bruschi; Alberico Borghetti
ISBN: 9783662009833 3662009838
OCLC Number: 851381833
Description: 1 online resource (xii, 271 pages 50 illustrations)
Contents: I: Function and Structure of Vascular Tissue --
Structure and Function of Resistance Vessels in Hypertension --
Vascular Smooth Muscle Cell in Hypertension: Dissecting Out Cause and Effect --
Cellular Mechanisms of Spontaneous Hypertension and Stroke: Role of Vascular Smooth Muscle Cells --
Hypertrophic Growth of Vascular Smooth Muscle --
Biomechanical and Electrical Responses of Normal and Hypertensive Veins to Short-Term Pressure Increases --
II: Calcium and Circulatory Control --
Dysfunction of Ca2+-pump of Vascular Muscle Membranes: An Important Etiological Factor in Hypertension --
Changes in Ca2+ and Ca2+ Sensitivity During Contraction-Relaxation of Arterial Muscle --
Superficial Sarcoplasmic Reticulum Regulates Activated and Steady-State Cytosolic Ca2+ Concentrations in Vascular Smooth Muscle --
Subsarcolemmal Increase in Intracellular Ca2+ in Vascular Muscle Cells from Spontaneously Hypertensive Rats --
Pathogenesis of Essential Hypertension: The Sodium Pump Inhibitor (Natriuretic Hormone) --
Sodium/Calcium Exchange --
Hypertension Hypothesis --
Calcium Metabolism and Its Relationship to Blood Pressure in Humans --
Parathyroids, Hypertension, and Vascular Reactivity --
Protection Against Hypertensive Cardiovascular Damage by Dihydropyridine Calcium Antagonists --
Nifedipine and Vascular Smooth Muscle Cells in Atherogenesis: In Vivo and In Vitro Studies --
Sodium/Calcium Exchange in Cultured Human Mesangial Cells --
III: Membrane Abnormalities: Blood Cell Models --
Relation of Cell Permeability to Salt Sensitivity in Hypertension --
RFLP Study of the SHR Genome in Relation to Cell Membrane Abnormalities --
Regulation on the Na+/H+ Exchanger in Essential Hypertension: Functional and Genetic Abnormalities --
Regulation of the Na+/H+ Exchanger by Protein Kinase C and Its Implications in Hypertension: The Platelet Model --
Phosphoinositide Metabolism in Hypertension --
Lymphocyte Membrane Abnormalities in Hypertension --
Structural and Functional Alterations of Platelet Membrane in Essential Hypertension --
Platelet Abnormalities in Human Hypertension --
Aldosterone Receptors and Effector Mechanisms in Mononuclear Leukocytes in Different Forms of Hypertension --
Role of Adrenergic Receptors in Essential Hypertension --
Na+, K+, CL? Cotransport System in Primary Hypertension: Studies in Red Cells and in the Choroid Plexus of Spontaneously Hypertensive Rats.
Responsibility: edited by Giacomo Bruschi, Alberico Borghetti.

Abstract:

The strength of this argument lies in the fact that peripheral vascular resistance is increased in all forms of hypertension and, in turn, the diameter of resistance vessels is the dominant factor in  Read more...

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