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Chemical biology : learning through case studies

Author: H Waldmann; Petra Janning
Publisher: Weinheim : Wiley-VCH, ©2009.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
Summary:

This first book to adopt a problem-based approach teaches the true basics of the subject through illustrated everyday case studies. The editor's extensive experience in writing textbooks and his  Read more...

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: H Waldmann; Petra Janning
ISBN: 9783527323302 3527323309
OCLC Number: 277069160
Description: xxxiii, 271 pages : illustrations (some color) ; 25 cm
Contents: Yeast-based chemical genomic approaches / Katja Hubel --
Microarray-based strategies to identify unknown protein / Sabine Borgmann and Christof M. Niemeyer --
Compound collection synthesis for chemical biology / Kamal Kumar --
Target identification and validation of a WNT/P-catenin pathway modulator / Petra Janning --
Activity-based protein profiling of cys proteases / Renier van der Hoorn --
The use of photoaffinity labeling for the identification of the binding site of the antibiotic linezolid / Rolf Breinbauer and Matthias Mentel --
Surgical strikes : uses of analog sensitive technologies to target kinases of interest / Matthias Rabiller and Daniel Rauh --
Modulation of protein-protein interactions by small molecules / Stefanie Bovens and Christian Ottmann --
Targeted protein degradation in live cells / Markus Kaiser --
Trapoxin B : from total synthesis to epigenetics / Bruno Bulic --
Native chemical ligation : a tool for chemical protein synthesis / Christian F.W. Becker --
Using split inteins to prepare semi-synthetic proteins and to study the mechanism of protein trans-splicing / Henning D. Mootz --
Elucidation of the ras cycle with semi-synthetic proteins / Luc Brunsveld --
The study of rab GTpase recycling using semi-synthetic prenylated proteins / Kirill Alexandrov [and others] --
Development of a model cancer vaccine candidate based on the MUC1 cellular surface glycopeptide epitope / Christian Hedberg and Ulrika Westerlind --
The introduction of chemical reporter groups by bioorthogonal ligation reactions for the imaging of cell-surface glycans / Rolf Breinbauer and Matthias Mental --
Sequence specific DNA-binding small molecules for protein recruitment and modulation of transcription / Hans-Dieter Arndt and Sascha Baumann --
G-quadruplex ligands as tools for elucidating c-MYC transcriptional regulation / Barbara Sacca and Markus Kaiser.
Responsibility: edited by Herbert Waldmann and Petra Janning.
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"This first book to adopt a problem-based approach teaches the true basics of the subject through illustrated everyday case studies. Each chapter introduces a different biological problem taken from Read more...

 
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