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Chemical carcinogens : activation mechanisms, structural and electronic factors, and reactivity

Author: Peter Politzer; F J Martin
Publisher: Amsterdam ; New York : Elsevier, 1988.
Series: Bioactive molecules, v. 5.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Since 1978, annual Interdisciplinary Cancer Research Workshops have been held at the University of New Orleans. In 1987 it seemed appropriate to consider an extended publication that would mark the  Read more...

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Genre/Form: Aufsatzsammlung
Document Type: Book
All Authors / Contributors: Peter Politzer; F J Martin
ISBN: 0444430083 9780444430083 0444426337 9780444426338
OCLC Number: 18191822
Description: xv, 366 pages : illustrations ; 25 cm.
Contents: 1. Metabolic and Chemical Activation of Carcinogens: An Overview (Y.T. Woo et al.). 2. Reactive Metabolites of Carcinogens and Their Interactions with DNA (A. Dipple). 3. DNA Adducts In Vitro and In Vivo (K. Hemminki). 4. Carcinogenic Halogenated Aliphatic Compounds (E.K. Weisburger). 5. Chemistry, Reactivity and Carcinogenicity of Chloro Ethers (B.L. Van Duuren, S.B. Van Duuren). 6. Carcinogenicity of Ethylene and its Derivatives: Structural Considerations (H.M. Bolt). 7. Reactions of Vinyl Chloride and its Metabolites with Bases in Nucleic Acids and the Potential Biological Consequences (B. Singer et al.). 8. Computational Studies of Olefin and Epoxide Carcinogenicity (P. Politzer). 9. Irregularities of DNA Structure and Their Effects on DNA Replication (L.S. Kan, P.O.P. Ts'o). 10. Nucleic Acid Alkylation by N-Nitroso Compounds Related to Organ-Specific Carcinogenesis (W. Lijinsky). 11. Nitro-Polycyclic Aromatic Hydrocarbons: Structural Features, Genotoxicity, and Risk Evaluation (R.W. Hart et al.). 12. Methyl Bay Region Diol Epoxides: Key Intermediates in the Metabolic Activation of Carcinogenic Methylated Polynuclear Aromatic Hydrocarbons (S.S. Hecht et al.). 13. Estrogen Carcinogenicity: Hormonal, Morphologic and Chemical Interactions (J.J. Li et al.). 14. Theoretical Implications of the k e Carcinogen-Screening Test (G. Bakale). 15. A Microspectrofluorometric Study of the Cell's Multiorganelle Detoxification Complex and Intracellular Carcinogen Interactions (E. Kohen et al.). Subject Index.
Series Title: Bioactive molecules, v. 5.
Responsibility: edited by P. Politzer and F.J. Martin, Jr.

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