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Chemical genomics

Author: Haian Fu
Publisher: Cambridge ; New York : Cambridge University Press, 2012.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"Advances in chemistry, biology, and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text with contributions from experts in the field discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of the basic  Read more...
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Document Type: Book
All Authors / Contributors: Haian Fu
ISBN: 9780521889483 0521889480
OCLC Number: 729574114
Description: xi, 345 pages : illustrations (some color) ; 29 cm
Contents: Harnessing the power of chemistry for biology and medicine / Cheryl L. Meyerkord and Haian Fu --
Exploring biology with small organic molecules / Nicholas Aberle and Craig M. Crews --
Chemical proteomics: a global study of protein-small molecule interactions / Akihisa Matsuyama, Yoko Yashiroda, and Minoru Yoshida --
Diversity-oriented synthesis / Warren R.J.D. Galloway [and others] --
Targeted chemical libraries / Gregory P. Tochtrop and Ryan E. Looper --
Fragment-based ligand discovery / Sandra Bartoli, Antonella Squarcia, and Daniela Fattori --
Basics and principles for building natural product-based libraries for HTS / Ronald J. Quinn --
Essentials for high-throughput screening operations / Stewart P. Rudnicki [and others] --
High content analysis and screening: basics, instrumentation, and applications / Paul A. Johnston --
Phenotypic screens with model organisms / Grant N. Wheeler, Robert A. Field, and Matthew L. Tomlinson --
Screening informatics and cheminformatics / Melinda I. Sosa [and others] --
Basics of HTS assay design and optimization / Eduard A. Sergienko --
Molecular sensors for transcriptional and post-transcriptional assays / Douglas S. Auld and Natasha Thorne --
Time-resolved fluorescence resonance energy transfer technologies in HTS / Yuhong Du and Jonathan J. Havel --
Compound profiling with high-content screening methodology / Thomas Mayer and Stephan Schürer --
Use of transgenic zebrafish in a phenotypic screen for angiogenesis inhibitors / Jaeki Min [and others] --
Flow cytometry multiplexed screening methodologies / Virginia M. Salas [and others] --
Label-free biosensor technologies in small molecule modulator discovery / Yuhong Du [and others] --
Basic principles and practices of computer-aided drug design / Chao-Yie Yang, Denzil Bernard, and Shaomeng Wang --
Computational approach for drug target identification / Honglin Li [and others] --
Pharmacogenomics to link genetic background with therapeutic efficacy and safety / Mark M. Bouzyk, Weining Tang, and Brian Leyland-Jones --
Drugs, genomic response signatures, and customized cancer therapy / Rafael Rosell, Teresa Moran, and Miguel Taron --
Current drug targets and the druggable genome / Margaret A. Johns, Andreas Russ, and Haian Fu.
Responsibility: edited by Haian Fu.

Abstract:

This text covers new techniques and applications in chemical genomics for researchers, professionals and graduates in biology, biomedicine and chemistry.  Read more...

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'Author Haian Fu has effectively assembled his textbook, Chemical Genomics, in a manner that is easy to comprehend and builds a basic understanding of chemical genomics.' Danielle Gerhard, Yale Read more...

 
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