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Cholesterol and presynaptic glutamate transport in the brain

Author: Tatiana Borisova, (Biochemist)
Publisher: New York, NY : Springer, ©2013.
Series: SpringerBriefs in neuroscience.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number of neurological and neurodegenerative disorders. Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport while unbalanced levels of cholesterol have been implicated in the pathogenesis of disorders such as stroke, ischemia, traumatic brain  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Borisova, Tatiana.
Cholesterol and presynaptic glutamate transport in the brain.
New York, NY : Springer, ©2013
(OCoLC)839397518
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Tatiana Borisova, (Biochemist)
ISBN: 9781461477594 146147759X 1461477581 9781461477587
OCLC Number: 852968138
Description: 1 online resource.
Contents: Presynaptic glutamate transport in the brain --
Cholesterol and its role in synaptic transmission --
Effects of cholesterol-depleting agent methyl-b-cyclodextrin (MbCD) on the functional state of brain nerve terminals --
The extracellular level and uptake of glutamate in cholesterol-deficient nerve terminals --
Unstimulated and exocytotic glutamate release from cholesterol-deficient nerve terminals --
Neuroprotection by lowering cholesterol.
Series Title: SpringerBriefs in neuroscience.
Responsibility: Tatiana Borisova.

Abstract:

This book presents data to address the extent to and way in which membrane cholesterol modulates presynaptic glutamate transport and whether lowering the level of cholesterol available can offer some  Read more...

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