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Cholesterol Metabolism, LDL, and the LDL Receptor : Low Density Lipoprotein and the L.D.L. Receptor.

Author: N Myant
Publisher: Oxford : Elsevier Science, 1990.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Cholesterol Metabolism, LDL, and the LDL Receptor.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Myant, N.
Cholesterol Metabolism, LDL, and the LDL Receptor : Low Density Lipoprotein and the L.D.L. Receptor.
Oxford : Elsevier Science, ©1990
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: N Myant
ISBN: 9780323148870 0323148875
OCLC Number: 843201612
Description: 1 online resource (480 pages)
Contents: Front Cover; Cholesterol Metabolism, LDL, and the LDL Receptor; Copyright Page; Table of Contents; Foreword: Simplifying Cholesterol Metabolism; Preface; Acknowledgments; Chapter 1 . The LDL Receptor in Perspective; Chapter 2. Cholesterol in Animal Tissues; I. Functions and Distribution; II. Sources of Cholesterol in Different Tissues; III. Measurement of Whole-Body Synthesis of Cholestero l; Chapter 3. HMG-CoA Reductase; I. The Rate-Limiting Step in Cholesterol Biosynthesis; II. Composition, Structure, and Orientation; III. The HMG-CoA Reductase Gene and Its mRNA. IV. Somatic-Cell Mutants in the Study of Cholesterol MetabolismV. The Regulation of HMG-CoA Reductase; Chapter 4. Acyl-CoA: Cholesterol Acyltransferase; I. Biological Functions; II. Properties and Methods of Assay; III. ACAT and the Metabolism of Intracellular Cholesteryl Esters; IV. Regulation of ACAT; References; Chapter 5. LDL: Physical and Chemical Characteristics; I. Composition and Physical Characteristics; II. Structure; III. Heterogeneity and Genetic Polymorphism; References; Chapter 6. Apolipoprotein B (apoB); I. LDL ApoB: Definition and Some Properties. II. ApoB Species in Human PlasmaIII. Composition and Structure of ApoB-100; IV. Lp(a): A Lipoprotein Containing ApoB-100; V. The LDL-Receptor-Binding Site on ApoB; VI. The ApoB Gene and Its mRNA; VII. Polymorphism in the Human ApoB Gene; VIII. Polymorphism in the ApoB Gene in Animals; IX. ApoB (Arg3 5 0 0-»Gln): A Rare Variant; X. Mutations Causing Absence or Deficiency of Plasma ApoB; References; Chapter 7. LDL: Origin and Metabolism; I. The Production of LDL; II. LDL Catabolism in Vivo; References; Chapter 8. The LDL Receptor: Biochemistry and Cell Biology; I. Historical Background. II. Surface Binding and Intracellular Degradation of LDLIII. LDL Receptors in Nonfibroblast Cells; IV. Effects of Growth Factors and Hormones in Vitro; References; Chapter 9. The LDL Receptor: Structure, Biosynthesis, and Molecular Genetics; I. The Route to Isolation of the Human Receptor and Its Gene; II. The Normal LDL Receptor; III. The LDL-Receptor Gene and Its Message; IV. Regulation of Expression of the Receptor Gene; VI. Somatic-Cell Mutations; V. Natural Mutations at the Receptor Locus; VII. Polymorphism in the LDL-Receptor Gene; VIII. Evolutionary Aspects of the Receptor Gene.

Abstract:

Cholesterol Metabolism, LDL, and the LDL Receptor.

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