skip to content
Clinical pharmacokinetic and pharmacodynamic drug interactions associated with antimalarials Preview this item
ClosePreview this item
Checking...

Clinical pharmacokinetic and pharmacodynamic drug interactions associated with antimalarials

Author: Tony K L Kiang; Kyle John Wilby; Mary H H Ensom
Publisher: [Cham] : Adis, [2015] ©2015
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

 

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Kiang, Tony K.L.
Clinical pharmacokinetic and pharmacodynamic drug interactions associated with antimalarials.
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Tony K L Kiang; Kyle John Wilby; Mary H H Ensom
ISBN: 9783319105277 3319105272
OCLC Number: 895047509
Description: 1 online resource
Contents: Introduction --
Pharmacology of Recommended Antimalarial Agents --
Drug Interaction Potential of Antimalarial Drugs Based on Known Metabolic Properties of Antimalarials --
Pharmacokinetic Drug Interactions Affecting Antimalarials --
Effects of Antimalarials on the Pharmacokinetics of Co-Administered Drugs --
Effects of Antimalarials on the Pharmacokinetics of Co-Administered Antimalarials --
Pharmacodynamic Interactions: Clinical Evidence for Combination Therapy, In Vitro Interactions, and In Vivo Interactions --
Limitations, Future Directions, and Conclusions.
Responsibility: Tony K.L. Kiang, Kyle John Wilby, Mary H.H. Ensom.

Abstract:

This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of the in vivo findings. Current limitations and gaps in the literature are summarized, and potential future research directions / experimentations are also suggested. In addition to the main objective to review the available clinical pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antimalarial drugs on the market today (i.e. chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, artemisinin, artemether, artesunate, dihydroartemisinin, artemotil, lumefantrine, primaquine, atovaquone, proguanil, piperaquine and quinine), this book also provides succinct chapter summaries on the epidemiology of malaria infection, diagnosis and therapeutics, in vivo pharmacology and chemistry, preclinical pharmacology, in vitro pharmacodynamics, in vitro reaction phenotyping, and in vitro drug-drug interaction data associated with the identified antimalarial drugs.

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/895047509> # Clinical pharmacokinetic and pharmacodynamic drug interactions associated with antimalarials
    a schema:CreativeWork, schema:Book, schema:MediaObject ;
    library:oclcnum "895047509" ;
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/sz> ;
    schema:about <http://dewey.info/class/616.9362061/e23/> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/2243647079#Topic/antimalarials_receptors_effect_of_drugs_on> ; # Antimalarials--Receptors--Effect of drugs on
    schema:about <http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medical_clinical_medicine> ; # MEDICAL--Clinical Medicine
    schema:about <http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medical_internal_medicine> ; # MEDICAL--Internal Medicine
    schema:about <http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medical_evidence_based_medicine> ; # MEDICAL--Evidence-Based Medicine
    schema:about <http://experiment.worldcat.org/entity/work/data/2243647079#Topic/antimalarials_pharmacokinetics> ; # Antimalarials--Pharmacokinetics
    schema:about <http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medicine_&_public_health> ; # Medicine & Public Health
    schema:about <http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medical_diseases> ; # MEDICAL--Diseases
    schema:about <http://experiment.worldcat.org/entity/work/data/2243647079#Topic/health_&_fitness_diseases_general> ; # HEALTH & FITNESS--Diseases--General
    schema:author <http://experiment.worldcat.org/entity/work/data/2243647079#Person/kiang_tony_k_l> ; # Tony K. L. Kiang
    schema:author <http://experiment.worldcat.org/entity/work/data/2243647079#Person/ensom_mary_h_h> ; # Mary H. H. Ensom
    schema:author <http://experiment.worldcat.org/entity/work/data/2243647079#Person/wilby_kyle_john> ; # Kyle John Wilby
    schema:bookFormat schema:EBook ;
    schema:datePublished "2015" ;
    schema:description "Introduction -- Pharmacology of Recommended Antimalarial Agents -- Drug Interaction Potential of Antimalarial Drugs Based on Known Metabolic Properties of Antimalarials -- Pharmacokinetic Drug Interactions Affecting Antimalarials -- Effects of Antimalarials on the Pharmacokinetics of Co-Administered Drugs -- Effects of Antimalarials on the Pharmacokinetics of Co-Administered Antimalarials -- Pharmacodynamic Interactions: Clinical Evidence for Combination Therapy, In Vitro Interactions, and In Vivo Interactions -- Limitations, Future Directions, and Conclusions."@en ;
    schema:description "This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of the in vivo findings. Current limitations and gaps in the literature are summarized, and potential future research directions / experimentations are also suggested. In addition to the main objective to review the available clinical pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antimalarial drugs on the market today (i.e. chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, artemisinin, artemether, artesunate, dihydroartemisinin, artemotil, lumefantrine, primaquine, atovaquone, proguanil, piperaquine and quinine), this book also provides succinct chapter summaries on the epidemiology of malaria infection, diagnosis and therapeutics, in vivo pharmacology and chemistry, preclinical pharmacology, in vitro pharmacodynamics, in vitro reaction phenotyping, and in vitro drug-drug interaction data associated with the identified antimalarial drugs."@en ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/2243647079> ;
    schema:genre "Electronic books"@en ;
    schema:inLanguage "en" ;
    schema:isSimilarTo <http://worldcat.org/entity/work/data/2243647079#CreativeWork/clinical_pharmacokinetic_and_pharmacodynamic_drug_interactions_associated_with_antimalarials> ;
    schema:name "Clinical pharmacokinetic and pharmacodynamic drug interactions associated with antimalarials"@en ;
    schema:productID "895047509" ;
    schema:url <https://link.springer.com/openurl?genre=book&isbn=978-3-319-10526-0> ;
    schema:url <http://link.springer.com/openurl?genre=book&isbn=978-3-319-10526-0> ;
    schema:url <http://ebookcentral.proquest.com/lib/ucm/detail.action?docID=1965464> ;
    schema:url <http://dx.doi.org/10.1007/978-3-319-10527-7> ;
    schema:url <http://link.springer.com/10.1007/978-3-319-10527-7> ;
    schema:url <http://www.myilibrary.com?id=765871> ;
    schema:url <http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=898796> ;
    schema:url <https://grinnell.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-10527-7> ;
    schema:url <http://public.eblib.com/choice/publicfullrecord.aspx?p=1965464> ;
    schema:workExample <http://worldcat.org/isbn/9783319105277> ;
    schema:workExample <http://dx.doi.org/10.1007/978-3-319-10527-7> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/895047509> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/2243647079#Person/ensom_mary_h_h> # Mary H. H. Ensom
    a schema:Person ;
    schema:familyName "Ensom" ;
    schema:givenName "Mary H. H." ;
    schema:name "Mary H. H. Ensom" ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Person/kiang_tony_k_l> # Tony K. L. Kiang
    a schema:Person ;
    schema:familyName "Kiang" ;
    schema:givenName "Tony K. L." ;
    schema:name "Tony K. L. Kiang" ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Person/wilby_kyle_john> # Kyle John Wilby
    a schema:Person ;
    schema:familyName "Wilby" ;
    schema:givenName "Kyle John" ;
    schema:name "Kyle John Wilby" ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Topic/antimalarials_pharmacokinetics> # Antimalarials--Pharmacokinetics
    a schema:Intangible ;
    schema:name "Antimalarials--Pharmacokinetics"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Topic/antimalarials_receptors_effect_of_drugs_on> # Antimalarials--Receptors--Effect of drugs on
    a schema:Intangible ;
    schema:name "Antimalarials--Receptors--Effect of drugs on"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Topic/health_&_fitness_diseases_general> # HEALTH & FITNESS--Diseases--General
    a schema:Intangible ;
    schema:name "HEALTH & FITNESS--Diseases--General"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medical_clinical_medicine> # MEDICAL--Clinical Medicine
    a schema:Intangible ;
    schema:name "MEDICAL--Clinical Medicine"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medical_diseases> # MEDICAL--Diseases
    a schema:Intangible ;
    schema:name "MEDICAL--Diseases"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medical_evidence_based_medicine> # MEDICAL--Evidence-Based Medicine
    a schema:Intangible ;
    schema:name "MEDICAL--Evidence-Based Medicine"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medical_internal_medicine> # MEDICAL--Internal Medicine
    a schema:Intangible ;
    schema:name "MEDICAL--Internal Medicine"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2243647079#Topic/medicine_&_public_health> # Medicine & Public Health
    a schema:Intangible ;
    schema:name "Medicine & Public Health"@en ;
    .

<http://worldcat.org/entity/work/data/2243647079#CreativeWork/clinical_pharmacokinetic_and_pharmacodynamic_drug_interactions_associated_with_antimalarials>
    a schema:CreativeWork ;
    rdfs:label "Clinical pharmacokinetic and pharmacodynamic drug interactions associated with antimalarials." ;
    schema:description "Print version:" ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/895047509> ; # Clinical pharmacokinetic and pharmacodynamic drug interactions associated with antimalarials
    .

<http://worldcat.org/isbn/9783319105277>
    a schema:ProductModel ;
    schema:isbn "3319105272" ;
    schema:isbn "9783319105277" ;
    .

<http://www.worldcat.org/title/-/oclc/895047509>
    a genont:InformationResource, genont:ContentTypeGenericResource ;
    schema:about <http://www.worldcat.org/oclc/895047509> ; # Clinical pharmacokinetic and pharmacodynamic drug interactions associated with antimalarials
    schema:dateModified "2018-01-05" ;
    void:inDataset <http://purl.oclc.org/dataset/WorldCat> ;
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.