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The combinatorial index

Author: Barry A Bunin
Publisher: San Diego : Academic Press, ©1998.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"Combinatorial chemistry has become a major focus of research activity for pharmaceutical, agrochemical, and biotechnology companies. The explosion of combinatorial methods has created the need for a compendium of reliable synthetic transformations from the primary literature. The Combinatorial Index fills this need. Included are chapters on linkers, solid-phase synthetic methods, analytical techniques, and solution  Read more...
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Genre/Form: Handbooks and manuals
Handbooks, manuals, etc
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Barry A Bunin
ISBN: 0121413403 9780121413408
OCLC Number: 38847491
Description: xvii, 322 pages : illustrations ; 26 cm
Contents: 1. Introduction --
2. Background --
3. Linkers for Solid-Phase Synthesis --
4. Combinatorial Solid-Phase Synthesis --
5. Analytical Methods for Solid-Phase Synthesis --
6. Preparation of Solution Libraries and Combined Approaches at the Solution/Solid-Phase Interface --
App. 1. Summary of Functional Group Transformations for Combinatorial Solid-Phase Synthesis --
App. 2. Classification of Heterocyclization Reactions --
App. 3. Unnatural Biopolymers --
App. 4. Oligosaccharides --
App. 5. List of Abbreviations.
Responsibility: Barry A. Bunin.
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Abstract:

With the explosion of combinatorial solid-phase methods, access to information has become one of the main barriers facing a synthetic chemist who is contemplating a combinatorial approach to a  Read more...

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"The Combinatorial Index provides a comprehensive collection of experimental protocols that will be of considerable practical utility to researcher working in the field of combinatorial chemistry. Read more...

 
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   schema:reviewBody ""Combinatorial chemistry has become a major focus of research activity for pharmaceutical, agrochemical, and biotechnology companies. The explosion of combinatorial methods has created the need for a compendium of reliable synthetic transformations from the primary literature. The Combinatorial Index fills this need. Included are chapters on linkers, solid-phase synthetic methods, analytical techniques, and solution libraries. Procedures from the literature for constructing combinatorial libraries of small molecules comprise an indispensable laboratory reference for the synthetic chemist. Each procedure in the compilation is preceded by a section entitled "Points of Interest," which highlights the strengths and limitations of the various methods. A structural appendix covers both functional group transformations and heterocyclization reactions in solid-phase synthesis. This comprehensive but easy-to-access guide to the combinatorial chemistry literature will save time on tedious library searches, introduce a growing audience of chemists to this exciting field, and lower the barriers to attempting a new or related methodology."--Jacket." ;
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