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Comparative pharmacokinetics

Author: J Edmond Riviere; Wiley InterScience (Online service)
Publisher: Chichester, West Sussex : Wiley-Blackwell, 2011.
Series: Veterinary Medicine Collection.
Edition/Format:   eBook : Document : English : 2nd editionView all editions and formats
Summary:
"Now in a newly revised edition, Comparative Pharmacokinetics presents the principles and techniques of pharmacokinetics in a detailed, yet practical and easily understandable manner. Coverage includes an overview of the basic physiologic processes of drug absorption and disposition and detailed explanation of pharmacokinetic means of measuring and predicting these processes by way of mechanistic and empirical  Read more...
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Genre/Form: Electronic books
Llibres electrònics
Additional Physical Format: Print version:
Riviere, J. Edmond (Jim Edmond).
Comparative pharmacokinetics.
Chichester, West Sussex : Wiley-Blackwell, 2011
(DLC) 2010047729
(OCoLC)680587256
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: J Edmond Riviere; Wiley InterScience (Online service)
ISBN: 9780470959916 0470959916 9780813829937 0813829933
OCLC Number: 705353420
Description: 1 online resource
Contents: Front Matter --
Introduction --
Principles of Drug Movement in the Body --
Quantitative Structure₆Permeability Relationships / Xin-Rui Xia --
Absorption --
Distribution / Jennifer Buur --
Renal Elimination --
Hepatic Biotransformation and Biliary Excretion / Ronald Baynes --
Compartmental Models --
Noncompartmental Models --
Nonlinear Models --
Physiological Models / Teresa Leavens --
Dosage Regimens --
Simultaneous Pharmacokinetic₆Pharmacodynamic Modeling / Pierre-Louis Toutain --
Study Design and Data Analysis / Jason Chittenden --
Bioequivalence Studies / Marilyn Martinez --
Population Pharmacokinetic Models / Jason Chittenden --
Dosage Adjustments in Disease States / Jennifer Davis --
Interspecies Extrapolations --
Tissue Residues and Withdrawal Times --
Index. Machine generated contents note: Preface. Chapter 1: Introduction. Chapter 2: Principles of Drug Movement in the Body. Chapter 3: Quantitative Structure Permeability Relationships (QSPeR). Chapter 4: Absorption. Chapter 5: Distribution. Chapter 6: Renal Elimination. Chapter 7: Hepatic Biotransformation and Biliary Excretion. Chapter 8: Compartmental Models. Chapter 9: Noncompartmental Models. Chapter 10: Nonlinear Models. Chapter 11: Physiological Models. Chapter 12: Dosage Regimens. Chapter 13: Simultaneous Pharmacokinetic-Pharmacodynamic Modeling. Chapter 14: Study Design and Data Analysis. Chapter 15: Design and Analysis of Bioequivalence Studies and FDA's in vitro/in vivo (IVIV). Chapter 16: Population Pharmacokinetic Models and the Bayesian Forecasting Applied to Clinical Pharmacokinetics. Chapter 17: Dosage Adjustments in Renal (and Hepatic) Disease. Chapter 18: Interspecies Extrapolations. Chapter 19: Tissue Residues and Withdrawal TimesAppendix.
Series Title: Veterinary Medicine Collection.
Responsibility: Jim E. Riviere, North Carolina State University, Raleigh, North Carolina.

Abstract:

Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed  Read more...

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"This book is helpful in understanding and designing pharmacokinetic studies, illustrating basic concepts and noting the species differences... The book does a good job of explaining a concept and Read more...

 
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