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| Material Type: | Internet resource |
|---|---|
| Document Type: | Book, Internet Resource |
| All Authors / Contributors: |
Ruth Nussinov; Gideon Schreiber |
| ISBN: | 9781420070057 1420070053 |
| OCLC Number: | 317249581 |
| Description: | xvii, 317 p., [8] p. of plates : ill. (some col.) ; 25 cm. |
| Contents: | Basic principles of protein-protein interaction / Joël Janin -- Low-resolution recognition factors determine major characteristics of the energy landscape in protein-protein interaction / Ilya A. Vakser -- The molecular architecture of protein-protein binding sites / Eric J. Sundberg -- Mapping protein function by combinatorial mutagenesis / Gábor Pál and Sachdev S. Sidhu -- The association of protein-protein complexes / Gideon Schreiber -- Computational simulations of protein-protein and protein-nucleic acid association / Georgi V. Pachov, Razif R. Gabdoulline, and Rebecca C. Wade -- Computational design of protein-protein interactions / Julia M. Shifman -- Protein-protein docking / Howook Hwang, Brian Pierce, and Zhiping Weng -- Prediction of protein interaction sites / Yanay Ofran -- Predicting molecular interactions in structural proteomics / Irina Kufareva and Ruben Abagyan -- Rearrangements and expansion of the domain content in proteins frequently increase the protein connectivity in the protein-protein interaction network / Inbar Cohen-Gihon, Roded Sharan, and Ruth Nussinov -- Intrinsically disordered proteins and their recognition functions / Vladimir N. Uversky ... [et al.] -- Identification of druggable hot spots on proteins and in protein-protein interfaces / Dmitri Beglov ... [et al.] -- Designing protein-protein interaction inhibitors / Matthieu Montes. |
| Responsibility: | edited by Ruth Nussinov, Gideon Schreiber. |
| More information: |
Abstract:
Often considered the workhorse of the cellular machinery, proteins are responsible for functions ranging from molecular motors to signaling. Presenting an overview of research directions, this book examines topics in the prediction of protein-protein interactions, including interference with protein-protein interactions and their design.
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Related Subjects:(9)
- Protein-protein interactions -- Computer simulation.
- Protein-protein interactions -- Mathematical models.
- Computersimulation.
- Mathematisches Modell.
- Protein-Protein-Wechselwirkung.
- Protein Interaction Mapping.
- Proteins -- physiology.
- Computational Biology -- methods.
- Models, Molecular.
