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Contraceptive risk : the FDA, Depo-Provera, and the politics of experimental medicine

Author: William Green
Publisher: New York : New York University, [2017]
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
"Depo-Provera is known as an injectable hormonal birth control method, but few are familiar with its dark and complicated history. Depo-Provera was tested on women since the mid-1960s without their informed consent until it was FDA-approved in 1992, but never FDA-approved as chemical castration for male sex offenders. Contraceptive risk is William Green's landmark study of Depo-Provera. Based on a fascinating  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Green, William, 1950-
Contraceptive risk.
New York : New York University, [2017]
(DLC) 2017003468
(OCoLC)961160724
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: William Green
ISBN: 9781479825929 1479825921
OCLC Number: 982287973
Description: 1 online resource.
Contents: Introduction : the odyssey of Depo-Provera --
The Grady Hospital study : the corruption of contraceptive research --
The twenty-five-year FDA approval controversy : cancer and the politics of acceptable risk --
Contraceptive chaos : unapproved use and Upjohn v. MacMurdo --
Marketing approval and litigation : osteoporosis and the realities of medical risk --
Chemical castration : the John Hopkins Clinic and People v. Gauntlett --
Conclusions : contraceptive drug risk failure, human dignity, and a duty to act.
Responsibility: William Green.

Abstract:

"Depo-Provera is known as an injectable hormonal birth control method, but few are familiar with its dark and complicated history. Depo-Provera was tested on women since the mid-1960s without their informed consent until it was FDA-approved in 1992, but never FDA-approved as chemical castration for male sex offenders. Contraceptive risk is William Green's landmark study of Depo-Provera. Based on a fascinating combination of archival materials and interviews, the book is framed as three interconnected stories told by Judith Weisz, who chaired the FDA's Public Board of Inquiry on Depo-Provera, a scientific court; by Anne MacMurdo who brought a products liability suit against Upjohn, the drug's manufacturer, for the deleterious side effects she suffered from the drug's use; and by Roger Gauntlett, an Upjohn heir who, when he was convicted of sexual assault, refused to take a dose of his family's own medicine as a probation condition. Together these three stories of Depo-Provera's convoluted fifty year odyssey call for a paradigm shift in pharmaceutical drug development. Contraceptive risk is a thoroughly researched and engrossing approach to the scientific, political and institutional forces involved in health law and policy, as well as the multifaceted politics of measuring risk"--Back cover.

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"By far the most thorough account of the Depo-Provera story to date. Though we may never get clear answers about whether Depo-Provera has done more harm than good over the past few decades, this Read more...

 
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