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Cryptosporidium : from molecules to disease

Author: Anthony Armson; Una M Ryan; R C A Thompson
Publisher: Amsterdam ; London : Elsevier, 2003.
Edition/Format:   Print book : EnglishView all editions and formats
In the relatively short period since <IT>Cryptosporidium</IT> was recognised as a human pathogen, and that it could be transmitted in water as well as directly between animals and people, it has been the subject of intense investigations. Its status as an opportunistic pathogen, especially in AIDS patients, and the lack of effective anti-cryptosporidial drugs have served to emphasise the public health  Read more...

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Document Type: Book
All Authors / Contributors: Anthony Armson; Una M Ryan; R C A Thompson
ISBN: 0444513515 9780444513519
OCLC Number: 53242169
Description: xlv, 422 pages : illustrations ; 25 cm
Contents: Section 1. Cryptosporidiosis : aetiology, infectivity and pathogenesis --
Cryptosporidium : they probably taste like chicken / Steve J. Upton 3 --
Cryptosporidium : from molecules to disease / Ronald Fayer 11 --
Cryptosporidium parvum : infectivity, pathogenesis and the host-parasite relationship / Cynthia L. Chappell, Pablo C. Okhuysen and A. Clinton White Jr. 19 --
What is the clinical and zoonotic significance of Cryptosporidium in domestic animals and wildlife / M.E. Olson [and others] 51 --
Section 2. Extended abstracts --
Control of Cryptosporidium parvum infection and the role of IL-4 in two strains of inbred mice / C.A. Notley [and others] 71 --
Human peripheral CD8+ CD103+ T-lymphocyte transmigration through inverted Cryptosporidium parvum sporozoite infected HCT-8 cell monolayers / G. Gargala [and others] 75 --
Cryptosporidium parvum volunteer study : infectivity and immunity / Cynthia L. Chappell [and others] --
Experimental transmission of human genotype 1 Cryptosporidium parvum into lambs / M. Giles [and others] 83 --
A longitudinal study of Cryptosporidium prevalence and its impact on performance in feedlot cattle / B.J. Ralston [and others] 85 --
Identification and characterisation of the antigenic Cpa135 protein / Fabio Tosini [and others] 87 --
A permanent method for detecting Cryptosporidium parvum life cycle stages in in vitro culture / H.V. Smith, R.A. Nichols and J.E. O'Grady 89 --
Successful cultivation of Cryptosporidium reveals previously undescribed gregarine-like developmental stages / N. Hijjawi [and others] 93 --
Section 3. Epidemiology and species differentiation --
Cryptosporidium as a public health challenge / R.M. Chalmers 97 --
The zoonotic potential of Cryptosporidium / R.C. Andrew Thompson 113 --
Molecular epidemiology of human Cryptosporidium / Lihua Xiao [and others] 121 --
Molecular characterization and taxonomy of Cryptosporidium / Una M. Ryan 147 --
Section 4. Extended abstracts --
Antigenic differences in Cryptosporidium parvum oocysts : the "Iowa strain" enigma / A. Ronald [and others] 163 --
Antigenic analysis of Cryptosporidium parvum isolates of human and animal origin / A. Ronald, J.E. O'Grady and H.V. Smith 165 --
Typing of Cryptosporidium parvum oocysts using phage-display technology / C. Lima [and others] 169 --
High resolution genotyping of Cryptosporidium by mutation scanning / Y. Abs El-Osta [and others] 173 --
Evaluation of oocyst DNA extraction methods using real-time PCR / Paul Monis [and others] 177 --
Differentiation of Cryptosporidium parvum subtypes by a novel microsatellite-telomere PCR with page / S.A. Blasdall, J.E. Ongerth and N.J. Ashbolt 181 --
Genotypic variation of Cryptosporidium organisms recovered from persons living in Kenya, Malawi, Vietnam and Brazil / W. Gatei [and others] 187 --
Epidemiological surveys of Cryptosporidium in Thai orphans / Mathirut Mungthin [and others] 191 --
Cryptosporidium and Cyclospora-associated diarrhea in Kathmandu, Nepal / Kazuo Ono [and others] 195 --
Ecology of zoonotic Cryptosporidium in watersheds containing cattle farming operations / T.K. Graczyk [and others] 199 --
Identifying variation among human, animal and environmental isolates of Cryptosporidium / R.M. Chalmers and K. Elwin 203 --
Cryptosporidium in eastern grey kangaroos Macropus giganteus / M.L. Power [and others] 207 --
Section 5. Viability and infectivity --
Detection of infectious Cryptosporidium parvum oocysts in environmental water samples / George D. Di Giovanni and Ramon Aboytes --
Measuring inactivation of Cryptosporidium parvum by in vitro cell culture / Paul A. Rochelle [and others] 225 --
In vitro cultivation and development of Cryptosporidium in cell culture / Nawal Hijjawi --
233 --
Section 6. Extended abstracts --
The use of cell culture and real-time PCR to assess disinfection of Cryptosporidium parvum / Alexandra Keegan [and others] 257 --
Inactivation of Cryptosporidium parvum oocysts by low pressure UV-light / P. Karanis, D. Schoenen and O. Hoyer 261 --
Detection of viable oocysyts of Cryptosporidium parvum by nucleic acid sequence based amplification (NASBA) / C.J. Lowery [and others] 265 --
Flow cytometry evaluation of Cryptosporidium parvum oocyst viability / A. Delaunaya [and others] 267 --
Section 7. Cryptosporidium and the environment --
The public health significance of Cryptosporidium in the environment / P.T. Monis and R.M. Chalmers 275 --
Assessing variables in disinfection parameters of Cryptosporidium parvum oocysts / Marilyn M. Marshall 279 --
Detection of Cryptosporidium oocysts in water matrices / Frank W. Schaefer III 285 --
Microbial health criteria for Cryptosporidium / Christobel Ferguson [and others] 295 --
Case-control studies of sporadic Cryptosporidium in Melbourne and Adelaide / B.R. Robertson [and others] 303 --
The DWI licensed inter-laboratory Cryptosporidium Proficiency Scheme (CRYPTS) / H.V. Smith, B.M. Campbell and J. Peet 307 --
Section 8. Extended abstracts --
Detection of Cryptosporidium spp. via fluorescent in situ hybridization : novel approaches of background reduction and signal enhancement / M. Dorsch and D.A. Deal 321 --
The risk of Cryptosporidium to Sydney's drinking water supply / Peter Cox [and others] 325 --
Outbreak of waterborne Cryptosporidium at North Battleford, SK, Canada / P. Wallis 341 --
Event sampling for Cryptosporidium and Giardia in South Australian water sources / Suzanne Hayes [and others] 345 --
Drinking water regulations for Cryptosporidium in England and Wales / David Drury and Anthony Lloyd 349 --
Why Cryptosporidium research for large water supplies : investigations in the Lake Mornos, the big water reservoir of greater Athens, Greece / P. Karanis [and others] 353 --
NATA accreditation of laboratories testing water for the presence of parasitic protozoa / T.G. Orlova 357 --
Use of ferric sulfate flocculation method for the recovery of Cryptosporidium oocysts from drinking water / P. Karanis and A. Kimura 361 --
A sensitive, semi-quantitative direct PCR-RFLP assay for simultaneous detection of five Cryptosporidium species in treated drinking waters and mineral waters / R.A.B. Nichols [and others] 363 --
The incidence of Cryptosporidium and Giardia in private water supples in the United Kingdom / John Watkins and David Drury 365 --
The problem with Cryptosporidium in swimming pools / G. Nichols [and others] 369 --
Development of a standard method to recover protozoan parasites from soft fruit and salad vegetables / C.A. Paton [and others] 371 --
How safe is drinking water in primary schools? / U. Chukohtuad and V. Suphiphat 375 --
Cryptosporidium parvum oocyst recovery using immunomagnetizable separation / C.A. Paton [and others] 377 --
Significance of enhanced morphological detection of Cryptosporidium sp. Oocysts in water concentrates using DAPI and immunofluorescence microscopy / H.V. Smith [and others] 381 --
Surveillance of Cryptosporidium : progressive approaches / G. Nichols [and others] 385 --
Cryptosporidium and the environment : overview and summary / Rachel M. Chalmers and Paul Monis 387 --
Section 9. Cryptosporidium : chemotherapy --
A review of chemotherapeutic approaches to the treatment of Cryptosporidium / Ar. Armson, J.A. Reynoldson and R.C.A. Thompson 395 --
Section 10. Extended abstracts --
An examination of the activity of the dinitroanilines on Cryptosporidium parvum using in vitro, in vivo and target expression methods / A. Armson [and others] 407 --
Nitazoxanide in the treatment of Cryptosporidium / J.F. Rossignol [and others] 411 --
The application of quantitative-PCR for high throughput screening of novel compounds against Cryptosporidium parvum in vitro and their subsequent IC50 determination / Louise Pallant [and others] --
Section 11. Synthesis --
Facilitators / Peter O'Donoghue [and others] 419.
Responsibility: edited by R.C. Andrew Thompson, Anthony Armson, Una M. Ryan.
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In the relatively short period since Cryptosporidium was recognised as a human pathogen, and that it could be transmitted in water as well as directly between animals and people, it has been the  Read more...


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    schema:description "In the relatively short period since Cryptosporidium was recognised as a human pathogen, and that it could be transmitted in water as well as directly between animals and people, it has been the subject of intense investigations. Its status as an opportunistic pathogen, especially in AIDS patients, and the lack of effective anti-cryptosporidial drugs have served to emphasise the public health importance of this organism. This has to some extent overshadowed the fact that Cryptosporidium is also an important pathogen of domestic animals and wildlife. In recent years, the application of molecular biology and culture techniques have had an enormous impact on our understanding of the aetiological agents of cryptosporidial infections and our ability to study the causative agents in the laboratory. As a consequence, a wealth of information and novel data has been produced during the last 3-4 years, particularly in the areas of taxonomy, biology, pathogenesis, epidemiology - particularly zoonotic and water borne transmission, and treatment. It is thus very timely to bring together in this book the international research community involved to review the major advances in research and identify the important research priorities for the future, thus enabling as wide an audience as possible to benefit from and share in this comprehensive look at Cryptosporidium and cryptosporidiosis."@en ;
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