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Cytochrome P450 2E1 : its role in disease and drug metabolism

Author: Aparajita Dey
Publisher: Dordrecht : Springer, ©2013.
Series: Sub-cellular biochemistry, v. 67.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1) which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities which include alcoholic liver disease, alcoholic pancreatitis,  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Dey, Aparajita.
Cytochrome P450 2E1 : Its Role in Disease and Drug Metabolism.
Dordrecht : Springer, ©2013
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Aparajita Dey
ISBN: 9789400758810 9400758812 9400758804 9789400758803
OCLC Number: 828302722
Description: 1 online resource (267 pages).
Contents: Cytochrome P450 2E1: Its Clinical Aspects and a Brief Perspective on the Current Research Scenario / Aparajita Dey --
Nrf2 and Antioxidant Defense Against CYP2E1 Toxicity / Arthur I. Cederbaum --
The Role of Cytochrome P450 2E1 in Ethanol-Mediated Carcinogenesis / Helmut K. Seitz, Xiang-Dong Wang --
The Importance of CYP2E1 in the Pathogenesis of Alcaoholic Liver Disease and Drug Toxicity and the Role of the Proteasome / Samuel W. French --
Relevance of CYP2E1 to Non-alcoholic Fatty Liver Disease / Ann K. Daly --
CYP2E1-Catalyzed Alcohol Metabolism: Role of Oxidant Generation in Interferon Signaling, Antigen Presentation and Autophagy / Natalia A. Osna, Terrence M. Donohue Jr. --
CYP2E1, Oxidative Stress, Post-translational Modifications and Lipid Metabolism / M. Raj Lakshman, Mamatha Garige --
The Role of CYP2E1 in Alcohol Metabolism and Sensitivity in the Central Nervous System / Claire Heit, Hongbin Dong, Ying Chen.
Series Title: Sub-cellular biochemistry, v. 67.
Responsibility: Aparajita Dey, editor.

Abstract:

The book examines clinical aspects of cytochrome P450 2E1(CYP2E1), covering clinical disorders associated with changes in the regulation of CYP2E1 and consequent abnormalities including alcoholic  Read more...

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