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The D-limited Mouse : a globally altered antibody repertoire shaped by the principle of CDR3 hydropathicity

Author: Gregory C Ippolito
Publisher: 2002.
Dissertation: Thesis (Ph. D.)--University of Alabama at Birmingham, School of Joint Health Sciences, 2002.
Edition/Format:   Thesis/dissertation : Thesis/dissertation : Manuscript   Archival Material : English
Database:WorldCat
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Material Type: Thesis/dissertation, Manuscript
Document Type: Book, Archival Material
All Authors / Contributors: Gregory C Ippolito
OCLC Number: 53196546
Description: xi, 95 leaves : ill. ; 29 cm.
Responsibility: by Gregory C. Ippolito.

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Evolutionary conservation of IgH D gene segments

by DFL16.1 (WorldCat user published 2009-10-08) Very Good Permalink

Gene targeted mice were made wherein the IgH locus of germline D gene segments (~ 80 kb) was deleted by Cre-loxP engineering in ES cells.  The locus was replaced by a single D gene element -- either germline DFL16.1 (encoding Tyr, Ser, and Gly) or an inverted DFL16.1 (encoding the charged residues...
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