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|Material Type:||Thesis/dissertation, Manuscript|
|Document Type:||Book, Archival Material|
|All Authors / Contributors:||
Gregory C Ippolito
|Description:||xi, 95 leaves : illustrations ; 29 cm|
|Responsibility:||by Gregory C. Ippolito.|
WorldCat User Reviews (1)
Evolutionary conservation of IgH D gene segments
Gene targeted mice were made wherein the IgH locus of germline D gene segments (~ 80 kb) was deleted by Cre-loxP engineering in ES cells. The locus was replaced by a single D gene element -- either germline DFL16.1 (encoding Tyr, Ser, and Gly) or an inverted DFL16.1 (encoding the charged residues...
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