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The D-limited Mouse : a globally altered antibody repertoire shaped by the principle of CDR3 hydropathicity

著者: Gregory C Ippolito
出版: 2002.
論文: Ph. D. University of Alabama at Birmingham, School of Joint Health Sciences 2002
エディション/フォーマット:   学位論文/卒業論文 : Thesis/dissertation : Manuscript   アーカイブ資料 : English
データベース:WorldCat
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資料の種類: Thesis/dissertation, Manuscript
ドキュメントの種類: 図書, アーカイブ資料
すべての著者/寄与者: Gregory C Ippolito
OCLC No.: 53196546
物理形態: xi, 95 leaves : illustrations ; 29 cm
責任者: by Gregory C. Ippolito.
その他の情報:

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Evolutionary conservation of IgH D gene segments

by DFL16.1 (投稿: 2009-10-08) 非常に良い パーマリンク

Gene targeted mice were made wherein the IgH locus of germline D gene segments (~ 80 kb) was deleted by Cre-loxP engineering in ES cells.  The locus was replaced by a single D gene element -- either germline DFL16.1 (encoding Tyr, Ser, and Gly) or an inverted DFL16.1 (encoding the charged residues...
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