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The D-limited Mouse : a globally altered antibody repertoire shaped by the principle of CDR3 hydropathicity

저자: Gregory C Ippolito
출판사: 2002.
논문: Ph. D. University of Alabama at Birmingham, School of Joint Health Sciences 2002
판/형식:   주제/주장 : 눈문/학위논문 : 필사본   아카이브 자료 : 영어
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자료 유형: 눈문/학위논문, 필사본
문서 형식: 책, 아카이브 자료
모든 저자 / 참여자: Gregory C Ippolito
OCLC 번호: 53196546
설명: xi, 95 leaves : illustrations ; 29 cm
책임: by Gregory C. Ippolito.
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WorldCat 사용자 리뷰 (1)

Evolutionary conservation of IgH D gene segments

by DFL16.1 (WorldCat 사용자가 게시함 2009-10-08) 아주 좋음 퍼머링크

Gene targeted mice were made wherein the IgH locus of germline D gene segments (~ 80 kb) was deleted by Cre-loxP engineering in ES cells.  The locus was replaced by a single D gene element -- either germline DFL16.1 (encoding Tyr, Ser, and Gly) or an inverted DFL16.1 (encoding the charged residues...
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