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Delivery technologies for biopharmaceuticals : peptides, proteins, nucleic acids and vaccines

Author: Lene Jørgensen; Hanne Mørck Nielsen
Publisher: Chichester, U.K. : Wiley, 2009.
Edition/Format:   Book : EnglishView all editions and formats
Database:WorldCat
Summary:

Successful delivery of biopharmaceuticals is a major challenge because their molecular properties lead to poor physical and chemical stability in the body and limited membrane permeability.

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Lene Jørgensen; Hanne Mørck Nielsen
ISBN: 9780470723388 0470723386 9780470688397 0470688394
OCLC Number: 421360726
Description: xx, 421 pages : illustrations ; 25 cm
Contents: Challenges in delivery of biopharmaceuticals; the need for advanced delivery systems / Hanne Mørck Nielsen and Lene Jorgensen --
Novel formulation approaches for peptide and protein injectables / Mingshi Yang and Sven Frokjaer --
Novel non-injectable formulation approaches of peptides and proteins / Shirui Mao, Dongmei Cun, and Yoshiaki Kawashima --
Chemical vectors for delivery of nucleic acid-based drugs / Elizabeth A. Vasievich and Leaf Huang --
Viral technology for delivery of nucleic acids / Shervin Bahrami and Finn Skou Pedersen --
The innate immune responses, adjuvants and delivery systems / S. Moein Moghimi --
Lipid nanoparticle-based systems for delivery of biomacromolecule therapeutics / Susana Martins, Domingos C. Ferreira, and Eliana B. Souto --
Dendrimers in delivery of biopharmaceuticals / Chandan Thomas and Fakhrul Ahsan --
Modification of peptides and proteins / Susanne Hostrup, Kasper Huus, and Henrik Parshad --
Nanocarriers for the delivery of peptides and proteins / Kenneth Lundstrom --
Polymer-based delivery systems for oral delivery of peptides and proteins / Bruno Sarmento, Domingos Ferreira, and Teófilo Vasconcelos --
Advanced pulmonary delivery of peptides or proteins using polymeric particles / Yu Seok Youn [and others] --
Polymer microparticles for nucleic acid delivery / Tim Pearce, Jared Hierman, and Chun Wang --
Pulmonary delivery of small interfering RNA for novel therapeutics / Qing Ge [and others] --
Lipid-based formulations for siRNA delivery / Camilla Foged, Pieter Vader, and Raymond M. Schiffelers --
Cellular bioavailability of peptide nucleic acids (PNAs) conjugated to cell penetrating peptides / Takehiko Shiraishi and Peter E. Nielsen --
DEAE-dextran-MMA graft copolymer for non-viral delivery of DNA / Yasuhiko Onishi, Yuki Eshita, and Masaaki Mizuno --
Liposomes in adjuvant systems for parenteral delivery of vaccines / Dennis Christensen [and others] --
Influenza virosomes as delivery systems for antigens / Mario Amacker [and others] --
GRAZAX : an oromucosal vaccine for treating grass pollen allergy with immunotherapy / Annette Rømmelmeyer Lundegaard, Lise Lund, and Jørgen Nedergaard Larsen --
Delivery technologies for biopharmaceuticals : a critical assessment / Marco van de Weert.
Responsibility: editors, Lene Jorgensen, Hanne Mørck Nielsen.

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