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Dendritic cells in cancer

Author: Michael R Shurin; Russell David Salter
Publisher: New York, NY : Springer, ©2009.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
It covers all aspects of DC generation, function, survival and antitumor activity in the tumor environment both in vivo and in experimental in vitro systems. The goal in focusing on a spectrum of issues related to DC in cancer is to provide an extensive and expansive review rather than a collection of independent analyses from different authors. Specific topics to be covered include analysis of DC behavior in the  Read more...
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Document Type: Book
All Authors / Contributors: Michael R Shurin; Russell David Salter
ISBN: 9780387886107 0387886109 9780387886114 0387886117 1441927840 9781441927842
OCLC Number: 263294417
Description: xvii, 396 pages : illustrations ; 25 cm
Contents: The central role of dendritic cells in immunity / Jessica Chu and Russell D. Salter --
Dendritic cells in cancer: emergence of the discipline / Michael R. Shurin and Michael T. Lotze --
Part I. Alterations of the dendritic cell system in cancer --
Tumor-infiltrating dendritic cells: the pathologist's perspective / Dmitry W. Gutkin --
Functional defects of dendritic cells in cancer / Mikhail M. Dikov and Irina S. Chekneva --
General properties of dendritic cell populations in cancer / Benjamin J. Daniel, Duane P. Jeansonne, Suzanne R. Thibodeaux, and Tyler J. Curiel --
Elimination of dendritic cells in cancer? Viktor Umansky and Dirk Schadendorf --
Part II. Mechanisms of dendritic cell dysfunction in cancer --
Tumor-derived factors responsible for dendritic cell dysfunction / Alberto Pinzon-Charry and J. Alejandro López --
Tumor-derived exosomes as dendritic cell modulators / Roberta Valenti [and others] --
Signaling pathways mediating dendritic cell dysfunction in cancer / Jing Yang and Qing Yi --
A role for STAT3 in dendritic cell regulation by tumor-derived factors / Dmitry I. Gabrilovich --
Tumor-associated inflammation and impact of dendritic cell function / Zoltan Pos [and others] --
Changes in dendritic cells in cancer and aging / Annabelle Grolleau-Julius and Raymond L. Yung --
Stress, immunity and dendritic cells in cancer / Rachel Kohman and Alexander W. Kusnecov --
Cancer therapy and dendritic cell immunomodulation / Galina V. Shurin, Neil Amina, and Michael R. Shurin. Part III. Role of dendritic cells in tumor escape --
Role IDO in dendritic cell differentiation and function in cancer / Alexey Popov and Joachim L. Schultze --
Dendritic cells: from inducers of specific T-cell responses to promoters of angiogenesis / George Coukos and Fabian Benencia --
Protumorigenic function of dendritic cells / Anjli Kukreja --
Dendritic cell maturation versus polarization in tumor escape / Michael W. Lipscomb, Walter J. Storkus, and Amy K. Wesa --
Part IV. Dendritic cells in cancer: clinical aspects --
Trafficking of dendritic cells in the tumor environment / Zoya R. Yurkovetsky and Ghena N. Yurkovetsky --
Dendritic cells in tumor-draining lymph nodes / Alistair J. Cochran [and others] --
Dendritic cell vaccines in cancer: obstacles to overcome / Ezra D. Mirvish, Rebecca G. Pomerantz, Louis D. Falo, and Larisa J. Geskin --
How best to generate dendritic cells from patients with cancer and how best to use them for immunotherapeutic purposes / Mark M. Aloysius, Richard A. Robins, and Oleg Eremin --
Genetically modified dendritic cells in cancer immunotherapy / Brian J. Morrison [and others] --
Dendritic cell tumors / Lourdes R. Ylagan --
Future directions in dendritic cell research in cancer / Madhav V. Dhodapkar.
Responsibility: Michael R. Shurin, Russell D. Salter, editors.

Abstract:

Dendritic cells play a key role in the immune response to cancer. This book covers all aspects of dendritic cell generation, function, survival and antitumor activity in the tumor environment both in  Read more...

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