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Design and analysis of animal studies in pharmaceutical development

Author: Shein-Chung Chow; Jen-pei Liu
Publisher: New York : Dekker, ©1998.
Series: Biostatistics (New York, N.Y.), 1.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
Summary:

Covers various statistical designs and methods used for animal studies in pharmaceutical research and development. This title demonstrates the correct way to interpret the results of animal studies  Read more...

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Document Type: Book
All Authors / Contributors: Shein-Chung Chow; Jen-pei Liu
ISBN: 9780824701307 0824701305
OCLC Number: 38745579
Description: x, 407 pages : illustrations.
Contents: Experimental design principles for animal studies in pharmaceutical development; interval estimation with small samples for Median Lethal Dose (LD50) or Median Effective Dose (ED50); principles in statistical testing in randomized toxicological studies; subacute toxicity studies - proof of safety versus proof of hazard; design of long-term carcinogenicity studies; analysis of long-term carcinogenicity studies; design of reproductive studies; analysis of reproductive and development studies; the in vitro Ames tests; the in vitro Chinese hamster ovary cell mutagenesis studies.
Series Title: Biostatistics (New York, N.Y.), 1.
Responsibility: edited by Shein-Chung Chow, Jen-pei Liu.
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." . .This book series will provide comprehensive and unified presentations of statistical designs and analyses of important applications in biostatistics. . .A well-balanced summary will be given of Read more...

 
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