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The design and analysis of clinical experiments

Author: Joseph L Fleiss
Publisher: New York : Wiley, 1999.
Series: Wiley classics library
Edition/Format:   Print book : English : Wiley classics library edView all editions and formats
Database:WorldCat
Summary:
This book shows how to choose between modern and classical competing designs for a clinical study -- such as crossover designs, multicenter studies, and repeated measure experiments -- how to carry out each design and analyze the resulting data. Provides many practical examples, end-of-chapter problems and references, and solutions to each problem. The mathematical bases are given for several design strategies as  Read more...
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Additional Physical Format: Online version:
Fleiss, Joseph L.
Design and analysis of clinical experiments.
New York : Wiley, 1999
(OCoLC)606354875
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Joseph L Fleiss
ISBN: 0471349917 9780471349914 0471820474 9780471820475
OCLC Number: 40698412
Notes: "A Wiley-Interscience publication."
Description: xiv, 432 pages : illustrations ; 23 cm.
Contents: 1. Reliability of measurement --
2. Simple linear regression analysis --
3. The parallel groups design --
4. Special cases of the parallel groups study --
5. Blocking to control for prognostic variables --
6. Stratification to control for prognostic variables --
7. Analysis of covariance and the study of change --
8. Repeated measurements studies --
9. Latin and Greco-Latin squares --
10. The crossover study --
11. Balanced incomplete block designs --
12. Factorial experiments --
13. Split-plot designs and confounding --
Appendix: Sample-size determination.
Series Title: Wiley classics library
Responsibility: Joseph L. Fleiss.
More information:

Abstract:

This book shows how to choose between modern and classical competing designs for a clinical study -- such as crossover designs, multicenter studies, and repeated measure experiments -- how to carry out each design and analyze the resulting data. Provides many practical examples, end-of-chapter problems and references, and solutions to each problem. The mathematical bases are given for several design strategies as well as for their analysis. Provides tables of critical values, 200 random permutations of the first one hundred integers, and an appendix on programmable methods for determining sample sizes.

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