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Design and Analysis of Vaccine Studies

Author: M Elizabeth Halloran; Jr Ira M Longini; Claudio J Struchiner
Publisher: New York, NY : Springer-Verlag New York, 2010.
Series: Statistics for Biology and Health
Edition/Format:   Computer file : English : Online-ausgView all editions and formats
Summary:

As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance,  Read more...

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Additional Physical Format: Erscheint auch als
Design, Analysis, and Interpretation of Vaccine Studies.
New York, NY : Springer Verlag New York, 2010
500 S.
Druck-Ausgabe
(DE-101)967882869
Material Type: Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: M Elizabeth Halloran; Jr Ira M Longini; Claudio J Struchiner
ISBN: 9780387686363 0387686363 9780387403137 0387403132
OCLC Number: 654401766
Reproduction Notes: Online-Ausg. Berlin [u.a.] Springer, 2010. online-Ressource.
Description: S.
Contents: and Examples.- Overview of Vaccine Effects and Study Designs.- Immunology and Early Phase Trials.- Binomial and Stochastic Transmission Models.- and Deterministic Models.- Evaluating Protective Effects of Vaccination.- Modes of Action and Time-Varying VE.- Further Evaluation of Protective Effects.- Vaccine Effects on Post-Infection Outcomes.- Household-Based Studies.- Analysis of Households in Communities.- Analysis of Independent Households.- Assessing Indirect, Total, and Overall Effects.- Randomization and Baseline Transmission.- Surrogates of Protection.
Series Title: Statistics for Biology and Health
Responsibility: by M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner.

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From the reviews:"...The first comprehensive book on the topic of vaccine trials, their design and analysis. Given the recent interest in developing vaccines, ...the book is timely, relevant and Read more...

 
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