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Designs for clinical trials : perspectives on current issues

Author: David P Harrington
Publisher: New York : Springer, ©2012.
Series: Applied bioinformatics and biostatistics in cancer research.
Edition/Format:   Print book : EnglishView all editions and formats
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This book examines current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of  Read more...

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Document Type: Book
All Authors / Contributors: David P Harrington
ISBN: 9781461401391 1461401399 9781461401407 1461401402
OCLC Number: 778837565
Description: xiv, 204 pages : illustrations.
Contents: New designs for phase I dose finding studies.- Phase II/III designs for trials.- Design issues for clinical studies with genomic measurements.- Designing studies with longitudinal measurements subject to dropout.- Issues in sample size re-estimation.- Adaptive designs.- The design of non-inferiority trials.- Issues in the design of HIV prevention trials.- Randomization algorithms.- Sequential designs for phase III studies.- Case studies of difficult designs.- Ethical issues in the design of trials.- Index.
Series Title: Applied bioinformatics and biostatistics in cancer research.
Responsibility: David Harrington, editor.

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