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Developmental biology

Author: E Edward Bittar; Neville Bittar
Publisher: Greenwich, Conn. : JAI Press, ©1998.
Series: Principles of medical biology, v. 11.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
The purpose of this module is to provide a survey of the rapidly expanding field of developmental biology and to introduce it to the student in a unifying way. In medical schools where courses in biochemistry, physiology, and pharmacology are already considerably intersecting, there is not surprisingly a rising demand in modern medical education for books emphasizing the interdisciplinary approach. In recent years,  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Developmental biology.
Greenwich, Conn. : JAI Press, ©1998
(DLC) 98018490
(OCoLC)38862835
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: E Edward Bittar; Neville Bittar
ISBN: 9781559388160 1559388161 9780080536125 0080536123
OCLC Number: 162597067
Description: 1 online resource (xiv, 332 pages) : illustrations.
Contents: 1. Control of the Cell Cycle --
2. Cell Lineage During Development --
3. Cadherin Cell Adhesion Molecules --
4. Epithelial Cell Polarity Development: Roles for The Membrane-Cytoskeleton and Cell Adhesion --
5. The Role of Extracellular Matrix during Development --
6. Gap Junctions --
7. Polypeptide Growth Factors in Vertebrate Embryogenesis --
8. Guidance of Developing Axons by Diffusible Chemoattractants --
9. Microtubule Organization in Growth Cones and Their Role in Pathfinding --
10. Development of the Neuromuscular Junction --
11. Somatomeres --
12. The Molecular and Cellular Biology of Skeletal Muscle Myogenesis: Practical Applications --
13. The Function of Hox Genes --
14. Mechanisms of Congenital Malformation.
Series Title: Principles of medical biology, v. 11.
Responsibility: edited by E. Edward Bittar, Neville Bittar.
More information:

Abstract:

The purpose of this module is to provide a survey of the rapidly expanding field of developmental biology and to introduce it to the student in a unifying way. In medical schools where courses in biochemistry, physiology, and pharmacology are already considerably intersecting, there is not surprisingly a rising demand in modern medical education for books emphasizing the interdisciplinary approach. In recent years, developmental biology has become a very vibrant and exciting field. The adoption of the interdisciplinary approach in this field has yielded enormous information about how DNA is able to produce a living organism from a fertilized egg. The discovery of 'master' genes in Drosophila that control spatial organization and share a segment of DNA, the so-called homeobox, and the discovery in C. elegans of genes controlling the timing of branching off of cell lineages are today recognized as milestones in molecular developmental biology. Because of space limitations and because of the information explosion, we have continued to pursue the policy of selecting broad topics but not in every case. This time, for example, though guided by the principle that a close connection exists between genes, adhesion, and morphogenesis, we opted to include certain topics such as cadherin - an adhesion molecule - rather than have the whole subject of adhesion dealth with in a single chapter. Substrate-adhering molecules (e.g., fibronectnin) are touched upon in Chapter 5. In a similar manner, only one type of junction is discussed at length. Chapters 8, 9, and 10 border on the extraordinary, for they are together absorbingly interesting. The last chapter makes things more pragmatic. The attention of the reader is drawn to the fact that several previous volumes of the compendium impinge on the present one. Chapters 25 and 26 in Volume 7B, in particular, have much to say on the subjects of extracellular matrix adhesion and intercellular communication.

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