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Dietary phosphorus : health, nutrition, and regulatory aspects

Author: Jaime Uribarri; Mona S Calvo
Publisher: Boca Raton, FL : CRC Press, Taylor & Francis Group, [2018]
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
"Phosphorus is an essential element occurring in most foods. In typical Western diets, it is not harmful but does adversely affect tissues in the body when given in excess or paucity. This book provides a comprehensive review of various aspects of phosphorus in relation to human nutrition."--Provided by publisher.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Dietary phosphorus.
Boca Raton : CRC Press, 2018
(DLC) 2017015227
(OCoLC)984742935
Print version:
DIETARY PHOSPHORUS.
[S.l.] : PRODUCTIVITY PRESS, 2017
(OCoLC)991765852
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Jaime Uribarri; Mona S Calvo
ISBN: 9781351645843 1351645846 9781315119533 1315119536 9781498706971 1498706975
OCLC Number: 1002207079
Description: 1 online resource (xv, 359 pages) : illustrations
Contents: Cover; Half title; Title Page; Copyright; Contents; Preface; Editor Bios; Contributors; Section I: Health Issues Associated with Dietary Phosphorus Intake; Chapter 1: Overview of Chronic Health Risks Associated with Phosphorus Excess; Abstract; Bullet Points; 1.1 Introduction; 1.2 Chronic Health Risks Associated with Phosphorus Excess; 1.2.1 Progression of Chronic Kidney Disease; 1.2.2 Mineral Bone Disease and Soft Tissue Calcifications; 1.2.3 Cardiovascular Disease; 1.2.4 Mortality; 1.2.5 Increased Anemia Risk; 1.2.6 Increased Cancer Risk; 1.3 Conclusions; References Chapter 2: Preclinical Evidence of the Nonskeletal Adverse Health Effects of High Dietary PhosphorusAbstract; Bullet Points; 2.1 Cancer, Diet, and Phosphorus Consumption; 2.1.1 The Significance of Diet to Cancer; 2.1.2 Dietary Inorganic Phosphate and Cancer; 2.1.3 Preclinical Models of Cancer; 2.2 Preclinical Evidence for a Modulating Effect of Phosphorus Consumption on Cancer; 2.2.1 Cell-Based Models Identify Increased Pi Availability as a Risk Factor for Cancer; 2.2.2 Dietary Pi Consumption and Carcinogen-Induced Skin Cancer; 2.2.3 Dietary Pi Consumption and Oncogene-Induced Lung Cancer 2.2.4 Relevance to Humans2.2.5 Dietary Pi as a Modulator of Cancer Initiation and Progression; 2.3 Cell Autonomous Effects of Phosphorus Availability on Cell Growth and Transformation; 2.3.1 Pi Availability and Cell Growth; 2.3.2 Increased Pi Availability Alters the Cellular and Molecular Phenotype; 2.3.3 Cell Transport and Sensing of Pi; 2.3.4 Slc20a1 and Cell Proliferation; 2.3.5 Slc34a2: A Novel Cancer Therapeutic Target; 2.4 Phosphorus-Responsive Endocrine, Paracrine, and Autocrine Factors and Cancer; 2.4.1 Dietary Pi-Responsive Endocrine Factors; 2.4.2 Vitamin D; 2.4.3 FGF23 2.4.4 Klotho2.4.5 Osteopontin; 2.5 Conclusions; Acknowledgments; References; Chapter 3: Clinical and Preclinical Evidence of the Skeletal and Vascular Adverse Health Effects of High Dietary Phosphorus; Abstract; Bullet Points; 3.1 Introduction; 3.2 Pathophysiology of Vascular Calcification; 3.2.1 Role of Phosphorus; 3.2.2 Role of PTH and Other Factors; 3.3 Pathophysiology of Bone Fragility in CKD; 3.3.1 Role of Phosphorus; 3.3.2 Role of PTH and Other Factors; 3.4 Vascular Calcification, Bone Health, and Survival: Lessons from Clinical and Preclinical Evidence; 3.4.1 Clinical Evidence 3.4.2 Preclinical Evidence3.5 Areas for Future Research; 3.6 Conclusions; References; Chapter 4: Associations between Phosphorus Intake and Mortality; Abstract; Bullet Points; 4.1 Introduction; 4.2 Phosphate Homeostasis in Humans: Nutritional Intake, Intestinal Absorption, and Renal Excretion; 4.3 Assessing Nutritional P Intake and P Balance: A Tough Goal in Research and Clinical Practice; 4.4 Phosphate and Mortality: Mechanisms; 4.5 Phosphate Intake and Mortality: Observational Studies; 4.6 Conclusions; References; Chapter 5: Phosphorus Intake and Whole-Body Phosphorus Homeostasis; Abstract
Responsibility: edited by Jaime Uribarri, Mona Calvo.

Abstract:

"Phosphorus is an essential element occurring in most foods. In typical Western diets, it is not harmful but does adversely affect tissues in the body when given in excess or paucity. This book provides a comprehensive review of various aspects of phosphorus in relation to human nutrition."--Provided by publisher.

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