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Directed molecular evolution of proteins, or, How to improve enzymes for biocatalysis

Author: Susanne Brakmann; Kai Johnsson; Wiley InterScience (Online service)
Publisher: Weinheim : Wiley-VCH, ©2002.
Edition/Format:   eBook : Document : EnglishView all editions and formats
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Susanne Brakmann; Kai Johnsson; Wiley InterScience (Online service)
ISBN: 3527600647 9783527600649 9783527304233 3527304231
OCLC Number: 61109527
Notes: This title is available on the World Wide Web. Editions may vary. Access is restricted to computers located within Mount Sinai or to those users eligible for remote access services.
Description: 1 online resource (xi, 357 pages) : illustrations
Contents: Ch. 1. Introduction, p. 1-3 / Kai Johnsson and Susanne Brakmann, p. 1-3 --
ch. 2. Evolutionary Biotechnology --
From Ideas and Concepts to Experiments and Computer Simulations / Peter Schuster, p. 5-28 --
ch. 3. Using Evolutionary Strategies to Investigate the Structure and Function of Chorismate Mutases / Donald Hilvert, Sean V. Taylor and Peter Kast, p. 29-62 --
ch. 4. Construction of Environmental Libraries for Functional Screening of Enzyme Activity / Rolf Daniel, p. 63-78 --
ch. 5. Investigation of Phage Display for the Directed Evolution of Enzymes / Patrice Soumillion and Jacques Fastrez, p. 79-110 --
ch. 6. Directed Evolution of Binding Proteins by Cell Surface Display: Analysis of the Screening Process / K. Dane Wittrup, p. 111-126 --
ch. 7. Yeast n-Hybrid Systems for Molecular Evolution / Brian T. Carter, Hening Lin and Virginia W. Cornish, p. 127-158 --
ch. 8. Advanced Screening Strategies for Biocatalyst Discovery / Andreas Schwienhorst, p. 159-175 --
ch. 9. Engineering Protein Evolution / Stefan Lutz and Stephen J. Benkovic, p. 177-213 --
ch. 10. Exploring the Diversity of Heme Enzymes through Directed Evolution / Patrick C. Cirino and Frances H. Arnold, p. 215-243 --
ch. 11. Directed Evolution as a Means to Create Enantioselective Enzymes for Use in Organic Chemistry / Manfred T. Reetz and Karl-Erich Jaeger, p. 245-279 --
ch. 12. Applied Molecular Evolution of Enzymes Involved in Synthesis and Repair of DNA / John F. Davidson, Jon Anderson, Haiwei Guo, Daniel Landis and Lawrence A. Loeb, p. 281-307 --
ch. 13. Evolutionary Generation Versus Rational Design of Restriction Endonucleases with Novel Specificity / Thomas Lanio, Albert Jeltsch and Alfred Pingoud, p. 309-327 --
ch. 14. Evolutionary Generation of Enzymes with Novel Substrate Specificities / Uwe T. Bornscheuer, p. 329-341.
Other Titles: How to improve enzymes for biocatalysis
Responsibility: edited by Susanne Brakmann and Kai Johnsson.
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