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DNA replication : damage from environmental carcinogens

Author: Huidong Zhang
Publisher: Dordrecht : Springer, 2015.
Series: SpringerBriefs in biochemistry and molecular biology.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing DNA damage. As we know, various environmental carcinogens are produced as a result of industry, agriculture, chemical  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Huidong Zhang
ISBN: 9789401772129 9401772126 9401772118 9789401772112
OCLC Number: 910159385
Description: 1 online resource : illustrations.
Contents: DNA replication --
Disturbances of the DNA replication system --
Fate of DNA replisome upon encountering DNA damage --
External Causes for DNA Damage --
Effect of environmental carcinogens on cellular physiology --
Protocols for studies of bypass of DNA damage by DNA polymerase.
Series Title: SpringerBriefs in biochemistry and molecular biology.
Responsibility: Huidong Zhang.

Abstract:

This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the  Read more...

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"It is focused on how environmental carcinogens affect DNA replication because it is well-known that correct DNA replication is the first crucial factor for the integrity of genetic informa-tion. ... Read more...

 
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