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Drug design of zinc-enzyme inhibitors : functional, structural, and disease applications

Author: Claudiu T Supuran; Jean-Yves Winum
Publisher: Hoboken, NJ : John Wiley & Sons, ©2009.
Series: Wiley series in drug discovery and development.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes. The second most abundant transition element in living organisms, zinc spans all areas of metabolism, with zinc-containing proteins offering both established and potential drug targets. Drug Design of Zinc-Enzyme Inhibitors brings together functional and structural information relevant to these zinc-containing  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Drup design of zinc-enzyme inhibitors.
Hoboken, N.J. : John Wiley & Sons, ©2009
(DLC) 2009005650
(OCoLC)304077458
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Claudiu T Supuran; Jean-Yves Winum
ISBN: 9780470508152 0470508159 9780470508169 0470508167 9780470275009 0470275006
OCLC Number: 502012584
Description: 1 online resource (xv, 1,022 pages, [32] pages of plates) : illustrations (some color).
Contents: DRUG DESIGN OF ZINC-ENZYME INHIBITORS; CONTENTS; PREFACE; CONTRIBUTORS; PART I INTRODUCTION; PART II DRUG DESIGN OF CARBONIC ANHYDRASE INHIBITORS AND ACTIVATORS; PART III DRUG DESIGN OF MATRIX METALLOPROTEINASE INHIBITORS; PART IV DRUG DESIGN OF BACTERIAL ZINC PROTEASE INHIBITORS; PART V DRUG DESIGN STUDIES OF OTHER ZINC-CONTAINING ENZYMES; Index.
Series Title: Wiley series in drug discovery and development.
Responsibility: edited by Claudiu T. Supuran, Jean-Yves Winum.

Abstract:

The book gives students and young researchers a resource on zinc enzymes, some of which were intensively studied for more than six decades and translated into model success stories of the  Read more...

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