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Drug discovery and development

Author: Mukund S Chorghade
Publisher: Hoboken, N.J. : Wiley-Interscience, ©2006-©2007.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
Summary:

This two volume set provides a comprehensive account of the entire sequence of operations involved in discovering a drug through the actual delivery of the drug to clinicians and medical  Read more...

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Mukund S Chorghade
ISBN: 9780471398462 0471398462 0471398489 9780471398486 9780471398479 0471398470
OCLC Number: 61178152
Description: 2 volumes : illustrations ; 26 cm
Contents: v. 1. Drug discovery [chapters 1-16] --
v. 2. Drug development [chapters 17-31]. From patent to prescription : paving the perilous path to profit / Richard J. Pariza --
Medicinal chemistry in the new millennium : a glance into the future / Paul W. Erhardt --
Contemporary drug discovery / Lester A. Mitscher, Apurba Dutta --
Combinatorial chemistry in the drug discovery process / Ian Hughes --
Parallel solution-phase synthesis / Norton P. Peet, Hwa-Ok Kim --
Timing of analog research in medicinal chemistry / János Fischer, Anikó Gere --
Possible alternatives to high-throughput screening / Camille G. Wermuth --
Proteomics and drug discovery / Susan Dana Jones, Peter G. Warren --
Using drug metabolism databases during drug design and development / Paul W. Erhardt --
Discovery of the antiulcer drug Tagamet / C. Robin Ganellin --
Discovery of potent nonpeptide vasopressin receptor antagonists / Bruce E. Maryanoff --
Discovery and development of the ultrashort-acting analgesic Remifentanil / Paul L. Feldman --
Discovery and development of Nevirapine / Karl Grozinger, John Proudfoot, Karl Hargrave --
Applications of nuclear imaging in drug discovery and development / John W. Babich, William C. Eckelman --
Polymeric sequestrants as nonabsorbed human therapeutics / Pradeep K. Dhal, Chad C. Huval, S. Randall Holmes-Farley --
Botanical immunomodulators and chemoprotectants in cancer therapy / Bhushan Patwardhan, Manish Gautam, Sham Diwanay --
Bioactive molecules in medicinal plants : a perspective on their therapeutic action / S.C. Taneja, G.N. Qazi --
Natural products as an inspiration for the discovery of new high-throughput chemical synthesis tools / Steven V. Ley, Ian R. Baxendale, Deborah A. Longbottom, Rebecca M. Myers --
Insulin sensitizers : emerging therapeutics / Braj B. Lohray, Vidya B. Lohray --
Criteria for industrial readiness of chiral catalysis technology for the synthesis of pharmaceuticals / Raymond McCague, Ian C. Lennon --
Enantioselective synthesis of propargyl alcohols as multifunctional synthons / J.S. Yadav, S. Chandrasekhar --
Carbohydrates : from chirons to mimics / G.V.M. Sharma, Palakodety Radha Krishna --
Meeting the challenges of process development and scale-up of active pharmaceutical ingredients / Yatendra Kumar, B. Vijayaraghavan --
Importance of polymorphs and salts in the pharmaceutical industry / Bipin Pandey, Vidya B. Lohray, Braj B. Lohray --
Role of outsourcing in drug manufacture / Peter Pollak --
Regulation-driven process chemistry / Shrikant V. Kulkarni --
Chemical process scale-up tools : mixing calculations, statistical design of experiments, and automated laboratory reactors / Andrei A. Zlota --
Library quality metrics / Richard L. Wife, Johan Tijhuis --
Tying a GABA from Copenhagen to Chicago : the chemistry of Tiagabine / Mukund S. Chorghade, Mahendra N. Deshpande, Richard J. Pariza --
Building contract research businesses based on integration of basic and applied research / Mukund S. Chorghade, Mukund K. Gurjar, C.V. Ramana, Sreenivas Punna --
Principles and practice of clinical drug development / Colin Scott.
Responsibility: edited by Mukund S. Chorghade.
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"...provides a nice survey of most of the key topics facing discovery houses today." (Doody's Health Services) "This reasonably priced book is well-written and produced. It has a useful 32-page Read more...

 
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