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Drug discovery handbook

Author: Shayne C Gad
Publisher: Hoboken, N.J. : Wiley-Interscience, ©2005.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Offers the techniques and methods in drug discovery, including genomics. This practical guide presents an explanation of proteomics, high throughput screening, and systems biology.

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Genre/Form: Handbooks and manuals
Handbooks, manuals, etc
Guides, manuels, etc
Additional Physical Format: Online version:
Drug discovery handbook.
Hoboken, N.J. : Wiley-Interscience, ©2005
(OCoLC)607736467
Online version:
Drug discovery handbook.
Hoboken, N.J. : Wiley-Interscience, ©2005
(OCoLC)609350479
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Shayne C Gad
ISBN: 0471213845 9780471213840
OCLC Number: 57001932
Description: xix, 1471 pages : illustrations ; 25 cm
Contents: Drug discovery in the 21st century: an introduction / Shayne C. Gad --
Natural products / Charles B. Spainhour --
Cancer cell proteomics using molecular aptamers / Weihong Tan, Zehui Cao, Dihua Shangguang --
Molecular similarity methods and QSAR models as tools for virtual screening / Jürgen Bajorath --
Systems biology: applications in drug discovery / Sean Ekins [and others] --
High throughput flow cytometry / Larry A. Sklar [and others] --
Combining NMR spectral information with associated structural features to form computationally non-intensive, rugged, and objective models of biological activity / Richard Beger, Dan A. Buzatu, Jon G. Wilkes --
Using Microsoft Excel as a laboratory data management tool / A. Erik Rubin, Mark F. Russo, William Neil --
The age of regulation / Sandy Weinberg, Gerald J. Whartenby --
Simultaneous screening of multiple cell lines using the CellCardtm system / Oren E. Beske --
Protein x-ray crystallography in drug discovery / Peter Nollert [and others] --
Biological and chemistry assays available during drug discovery and developability assessment / Duane B. Lakings --
Strategies and methods in monitoring and targeting protein-protein interactions / Arianna Loregian, Giorgio Palù --
High throughput screening: evolution of technology and methods --
Martyn N. Banks [and others] --
Metal-enhanced fluorescence: application to high-throughput screening and drug discovery / Kadir Aslan . [et al,] --
Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays / Brian J. Eastwood [and others] --
Coupled luminescent methods in drug discovery: three-minute assays for cytotoxicity and phosphatase activity / Michael J. Corey, Robert J. Kinders --
Design and pharmaceutical applications of prodrugs / Tomi Jarvinen [and others] --
GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders / Ulf Madsen [and others] --
Cardiac sarcolemmal ATP-sensitive potassium channel antagonists: novel ischemia-selective antiarrhythmic agents / George E. Billman --
Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid and anti-coagulant therapies for sepsis / Peter C. Minneci [and others] --
Combinatorial chemistry in the drug discovery process / Nathan T. Ross, Brian R. McNaughton, Benjamin L. Miller --
Herbal medicines and animal models of gastrointestinal diseases / C.H. Cho, J.K.S. Ko --
Endocrine and metabolic agents / Brian L. Furman --
Respiratory viruses / Paul D. Olivo --
Strategies in the design of antiviral drugs / Erik De Clercq, Piet Herdewijn --
Protein kinase inhibitors in drug discovery / Keykavous Parang, Gongqin Sun --
RNA-based therapies / Ingmar Hoerr, Steve Pascolo --
Novel imaging agents for molecular MR imaging of cancer / Dmitri Artemov, Zaver M. Bhujwalla --
Genomics-based drug discovery / Spyro Mousses --
Cancer drug discovery / Susan Mooberry.
Responsibility: edited by Shayne Cox Gad.
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"...provides in one volume most of the currently used and emerging technologies available...presents a wealth of information on topics that are difficult to find elsewhere...a very useful handbook." Read more...

 
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