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详细书目
| 材料类型: | 互联网资源 |
|---|---|
| 文件类型: | 书, 互联网资源 |
| 所有的著者/提供者: |
Ziwei Huang |
| ISBN: | 9780471672005 0471672009 |
| OCLC号码: | 85498729 |
| 描述: | xix, 521 p., [16] p. of plates : ill. (some col.) ; 25 cm. |
| 内容: | Molecular docking and structure-based design / P. Therese Lang ... [et al.] -- Recent advances in drug discovery research using structure-based virtual screening techniques : examples of success for diverse protein targets / Sutapa Ghosh ... [et al.] -- Virtual screening in drug discovery / Malcolm J. McGregor, Zhaowen Luo, and Xuliang Jiang -- Computer-aided drug design / Grace Shiahuy Chen and Ji-Wang Chern -- Focused library design based on hit and target structures : method and application in drug discovery / Weiliang Zhu ... [et al.]. Beyond natural products : synthetic analogs of bryostatin 1 / Paul A. Wender ... [et al.] -- The promises and pitfalls of small-molecule inhibition of poly(ADP-ribose) glycohydrolase (PARG) / Amanda C. Nottbohm and Paul J. Hergenrother -- Cyclic ADP-ribose analogues with minimal structure : synthesis and calcium-release activity / Lihe Zhang and Andreas H. Guse -- Evaluation of neuroimmunophilin ligands / Junhai Xiao, Aihua Nie, and Song Li -- Chiral drugs and the associated asymmetric synthesis / Jiange Zhang and Guoqiang Lin. Alpha-helix mimetics in drug discovery / Hang Yin, Gui-In Lee, and Andrew D. Hamilton -- Basic and translational research of chemokine ligands and receptors and development of novel therapeutics / Won-Tak Choi ... [et al.] -- Research progress in protein post-translational modification / Jia Hu, Yanting Guo, and Yanmei Li -- Controlled release of antibiotics encapsulated in nanoporous sol-gel materials with tunable pore parameters / Houping Yin, Laura Zheng, and Yen Wei -- Retinoic acid and arsenic trioxide treatment in acute promyelocytic leukemia : a model of oncoprotein targeted therapy / Jian-Hua Tong, Sai-Juan Chen, and Zhu Chen. 2-chlorodeoxyadenosine (cladribine) : rational development of a novel chemotherapeutic agent / Howard B. Cottam and Dennis A. Carson -- Apoptosis-based drug discovery for cancer / John C. Reed ... [et al.] -- Mechanism-based development of memantine as a therapeutic agent in treating Alzheimer's disease and other neurologic disorders : low-affinity, uncompetitive antagonism with fast off-rate / Huei-Sheng Vincent Chen and Stuart A. Lipton -- Bridging bench to clinic : roles of animal models for post-genomics drug discovery on metabolic diseases / Chi-Wai Wong and Ling Chen -- Stem cell research and applications for human therapies / Prithi Rajan ... [et al.]. |
| 责任: | edited by Ziwei Huang. |
| 更多信息: |
摘要:
This book explores and discusses some of the most important topics in post-genomics life and biopharmaceutical sciences such as pharmacogenomics, chemical genomics, chemical biology, structural genomics, drug discovery, biophysics and bioengineering with various chapters contributed by experts in respective fields.
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出版商概要
"A valuable resource for scientists ... Chapters in each section are filled with in-depth biological and chemical data and, importantly, include worked examples of drugs identified from these approaches." (The Biochemist, October 2008) "..the book achieves the objective of the Editor in providing a useful tool and reference for scientists concerned with state-of-the-art postgenomic drug discovery...this book will be of interest to medicinal chemistry, as well as to other concerned with developing new drug products." (Journal of Medicinal Chemistry, January 2008) 再读一些...
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添加标签 目的是为 "Drug discovery research : new frontiers in the post-genomic era".
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