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Drug Efficacy, Safety, and Biologics Discovery : Emerging Technologies and Tools

Author: Sean Ekins; Jinghai J Xu
Publisher: Hoboken, N.J. : John Wiley & Sons, ©2009.
Series: Wiley series on technologies for the pharmaceutical industry.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
This book covers key emerging technologies - detailed under About the Topic - in pharmaceutical R & D and how they have substantially impacted (or are currently impacting) drug discovery. The cross-disciplinary collaborations implicit in integrating these technologies with drug discovery operations will fuel the engine for future innovations. This book cuts across the multiple areas of drug discovery, each chapter  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Drug efficacy, safety, and biologics discovery.
Hoboken, N.J. : John Wiley & Sons, ©2009
(DLC) 2008036264
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Sean Ekins; Jinghai J Xu
ISBN: 9780470431801 0470431806 9780470431818 0470431814
OCLC Number: 647763279
Description: 1 online resource (xvi, 408 pages, [16] pages of plates) : illustrations (some color).
Contents: Focus on the fundamentals : toward better therapeutic index prediction / Jinghai J. Xu and Li J. Yu --
High-throughput protein-based technologies and computational models for drug development, efficacy, and toxicity / Leonidas G. Alexopoulos, Julio Saez Rodriguez, and Christopher W. Espelin --
Cellular systems biology applied to preclinical safety testing : a case study of CellCiphr profiling / Lawrence Vernetti [and others] --
Systems pharmacology, biomarkers, and biomolecular networks / Aram S. Adourian [and others] --
Zebrafish models for human diseases and drug discovery / Hanbing Zhong, Ning-Ai Liu, and Shuo Lin --
Toxicity pathways and models : mining for potential side effects / Sean Ekins and Josef Scheiber --
Computational systems biology modeling of dosimetry and cellular response pathways / Qiang Zhang [and others]. Stem cell technology for embryotoxicity, cardiotoxicity, and hepatotoxicity evaluation / Julio C. Davila [and others] --
Telemetry technology for preclinical drug discovery and development / Yi Yang --
Nanotechnology to improve oral drug delivery / Mayank D. Bhavsar, Shardool Jain, and Mansoor M. Amiji --
Functional glycomics and the future of glycomic drugs / Ram Sasisekharan and Karthik Viswanathan --
Modeling efficacy and safety of engineered biologics / Jeffrey R. Chabot and Bruce Gomes --
Regulation of gene expression by small, non-coding RNAS : practical applications / Roman Herrara and Eric Tien --
Future perspectives of biological engineering in pharmaceutical research : the paradigm of modeling, mining, manipulation, and measurements / Jinghai J. Xu [and others].
Series Title: Wiley series on technologies for the pharmaceutical industry.
Responsibility: edited by Sean Ekins, Jinghai J. Xu.

Abstract:

This book covers key emerging technologies - detailed under About the Topic - in pharmaceutical R & D and how they have substantially impacted (or are currently impacting) drug discovery. The  Read more...

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