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Drug membrane interactions : analysis, drug distribution, modeling

Author: J K Seydel
Publisher: Weinheim : Wiley-VCH, 2002.
Series: Methods and principles in medical chemistry, 15.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Barrier, reservoir, target site - those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism. A detailed knowledge of lipid membranes and of the various modes of drug-membrane interaction is therefore the prerequisite for a better understanding of drug action. Many of today's pharmaceuticals are amphiphilic or catamphiphilic, enabling them to  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Seydel, J.K. (Joachim Karl).
Drug-membrane interactions.
Weinheim : Wiley-InterScience, ©2002
(OCoLC)49635333
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: J K Seydel
ISBN: 9783527600632 3527600639
OCLC Number: 62392596
Description: 1 online resource (approximately 354 pages) : illustrations.
Contents: Drug-Membrane Interactions; Contents; Preface; Foreword; Introduction; 1 Function, Composition, and Organization of Membranes; 2 Octanol-Water Partitioning versus Partitioning into Membranes; 3 Analytical Tools for the Analysis and Quantification of Drug-Membrane Interactions; 4 Drug-Membrane Interaction and Pharmacokinetics of Drugs; 5 Drug-Membrane Interactions and Pharmacodynamics; 6 Computer Simulation of Phospholipids and Drug-Phospholipid Interactions; Index.
Series Title: Methods and principles in medical chemistry, 15.
Responsibility: Joachim K. Seydel, Michael Wiese ; eds.: Raimund Mannhold [and others].
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Abstract:

Surveys crucial membrane properties and presents techniques to elucidate drug-membrane interactions, including computer-aided predictions. This volume discusses the effects of membrane interaction on  Read more...

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