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Drug metabolism and transport : molecular methods and mechanisms

Author: Lawrence H Lash
Publisher: Totowa, N.J. : Humana Press, ©2005.
Series: Methods in pharmacology and toxicology.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors  Read more...

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Lawrence H Lash
ISBN: 1588293246 9781588293244 1592598323 9781592598328
OCLC Number: 55633558
Description: x, 387 pages : illustrations ; 24 cm.
Contents: Renal cytochrome P450s and flavin-containing monooxygenases : potential roles in metabolism and toxicity of 1,3-butadiene, trichloroethylene, and tetrachloroethylene / Adnan A. Elfarra --
Experimental approaches for the study of cytochrome P450 gene regulation / Hollie I. Swanson [and others] --
Insulin and growth factor signaling : effects on drug metabolizing enzymes / Sang K. Kim, Kimberly J. Woodcroft, and Raymond F. Novak --
Catalytic function and expression of glutathione transferase zeta / Philip G. Board, M.W. Anders, and Anneke C. Blackburn --
Glucuronidation of fatty acids and prostaglandins by human udp glucuronosyltransferases / Anna Radominska-Pandya, Joanne M. Little and Arthur Bull --
Transcriptional regulation of UDP-glucuronosyltransferases / Anna Radominska-Pandya, Peter I. Mackenzie, and Wen Xie. Phenotypic and genotypic characterization of n-acetylation / Craig K. Svensson and David W. Hein --
Methods and approaches to study metabolism and toxicity of acetaminophen / Sam A. Bruschi --
Modulation of drug metabolism and antiviral therapies / Bernhard H. Lauterburg --
Modulation of thiols and other low-molecular-weight cofactors : effects on drug metabolism and disease susceptibility / Charles V. Smith --
Multidrug resistance proteins and hepatic transport of endo- and xenobiotics / Phillip M. Gerk and Mary Vore --
Structural determinants of folate and antifolate membrane transport by the reduced folate carrier / Wei Cao and Larry H. Matherly --
Glutathione transport in the kidneys : experimental models, mechanisms, and methods / Lawrence H. Lash --
Human cytosolic sulfotransferases : properties, physiological functions, and toxicology / Charles N. Falany.
Series Title: Methods in pharmacology and toxicology.
Responsibility: edited by Lawrence H. Lash.
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"With the diverse subject matter and the wealth of information on techniques and research strategies there is likely to be something in this book to interest those from PhD students to more Read more...

 
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