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Drug resistance in the treatment of cancer

Author: H M Pinedo; Giuseppe Giaccone
Publisher: Cambridge, U.K. ; New York : Cambridge University Press, ©1998.
Series: Cancer, clinical science in practice.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
Summary:

International authorities review the mechanisms and clinical implications of drug resistance in cancer.

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: H M Pinedo; Giuseppe Giaccone
ISBN: 0521473217 9780521473217
OCLC Number: 36470679
Description: xvi, 323 pages : illustrations ; 24 cm.
Contents: Resistance mechanisms to antimetabolites --
Resistance to antitumor alkylating agents and cisplatin --
The MDR genes --
Topoisomerase genes and resistance to topoisomerase inhibitors --
Genes that modulate apoptosis: major determinatns of drug resistance --
Clinical implications of drug resistance --
The reversal of multidrug resistance --
Effect of dose and schedule on chemotherapeutic drug resistance --
Circumvention of drug resistance by high-dose chemotherapy in solid tumors --
Enhancing drug effectiveness by gene transfer.
Series Title: Cancer, clinical science in practice.
Responsibility: edited by Herbert M. Pinedo and Giuseppe Giaccone.
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'... recommended for clinical oncologists, who will find extensive information on this topic which is seldom to be found in oncology textbooks.' Annals of Oncology 'The strength of the book is Read more...

 
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