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Endometrial cancer : current epidemiology, detection and management

Author: Samir A Farghaly
Publisher: New York : Nova Science Publishers, Inc., [2015] ©2015
Series: Cancer etiology, diagnosis, and treatments.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Endometrial cancer is the most common cancer of the female reproductive system, with more than 49,500 United States women that are diagnosed with the disease each year. It tends to develop after menopause, when a woman is between the ages of 50 and 60. It is the sixth most common cancer in women worldwide (fourteenth most common cancer overall), with 320,000 new cases diagnosed in 2012, and it is the 13th most  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Farghaly, Samir A.
Endometrial Cancer : Current Epidemiology, Detection and Management
Hauppauge : Nova Science Publishers, Inc.,c2015
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Samir A Farghaly
ISBN: 9781634631945 1634631943
OCLC Number: 900464411
Description: 1 online resource : illustrations (some color)
Contents: ENDOMETRIAL CANCER: CURRENT EPIDEMIOLOGY, DETECTION AND MANAGEMENT; ENDOMETRIAL CANCER: CURRENT EPIDEMIOLOGY, DETECTION AND MANAGEMENT; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Epidemiology of Endometrial Cancer; Abstract; Concepts in Cancer Epidemiology; Descriptive Epidemiology of Endometrial Cancer; Aetiology of Endometrial Cancer; Conclusion; References; Chapter 2: Endometrial Cancer and Its Precursor Lesions: Histopathologic and Molecular Aspects; Abstract; Introduction; Type I Endometrial Carcinoma; Endometrioid Adenocarcinoma Precursor lesions of Type I Endometrial CarcinomaEndometrial Hyperplasia; Simple Hyperplasia; Complex Hyperplasia; Atypical Hyperplasia; Endomtrial Intraepithelial Neoplasia; Molecular Features; Microsatellite Instability (MSI); PTEN; RAS-RAF-MEK-ERK Signaling Pathway; PIK3CA; β-Catenin Gene (CTNNB1); Type II Endometrial Carcinoma; Endometrial Serous Carcinoma; Precursor Lesion of Endometrial Serous Carcinoma; Endometrial Intraepithelial Carcinoma (EIC); Endometrial Glandular Dysplasia (EGD); Molecular Features; TP53; Her-2/Neu; EGFR; Clear Cell Carcinoma Carcinosarcoma (Malignant Mixed Mullerian Tumor)Conclusion; References; Chapter 3: Molecular Pathologic Aspects of Endometrial Cancer: An Update; Abstract; Introduction; Trefoil Factor Family-3 (TFF3); Aldolase C, Hypoxia-Inducible Factor (HIF1 α); 14-3-3 Sigma; Prostate Specific Membrane Antigen (PSMA); Pair Box-8 (PAX8); Transformation Growth Factor β (TGFβ),; Ski and DAB2; Glucose Regulated Protein 78 (GRP78); The Cancer Genome Altas Research Network; Conclusion; References; Chapter 4: Endometrial Endometrioid Adenocarcinoma: Histology, Precursors and Molecular Alterations; Abstract Introduction1. Precursors of Endometrioid Adenocarcinoma; 1.1. Background; 1.2. Histology; 1.3. Progression; 1.4. Histologic Challenges; 1.5. Histologic Changes and Follow-Up after Progesterone Treatment; 2. Endometrioid Adenocarcinoma; 2.1. Background; 2.2. Histology; 2.3. Differential Diagnosis; 2.4. Staging Endometrioid Adenocarcinoma; 2.5. Pitfalls, Controversies, and Conundrums; 3. Molecular Changes; Conclusion; References; Chapter 5: Hereditary Endometrial Cancer; Abstract; 1. Introduction; 2. Lynch Syndrome; 3. Muir Torre Syndrome; 4. Peutz Jeghers Syndrome; 5. Cowden Syndrome 6. Carcinoma of the Lower Uterine Segment7. BRCA1/2 Mutation Related Cancers; Conclusion; References; Chapter 6: Lynch Syndrome and Endometrial Cancer; Abstract; Introduction; Molecular Bases; Endometrium Cancer Risk in Lynch Syndrome; Clinicopathologic Features; Diagnosis and Treatment; Screening; Chemoprevention; Risk-Reducing Surgeries; Conclusion; References; Chapter 7: Sentinel Lymph Nodes in Endometrial Cancer; Abstract; Introduction; Mapping Techniques; Cervical Injection; Subserosal Injection; Hysteroscopic Injection; Histopathological Assessment of Sentinel; Lymph Nodes; Conclusion
Series Title: Cancer etiology, diagnosis, and treatments.
Responsibility: Samir A. Farghaly, M.D., Ph.D., editor.

Abstract:

Endometrial cancer is the most common cancer of the female reproductive system, with more than 49,500 United States women that are diagnosed with the disease each year. It tends to develop after menopause, when a woman is between the ages of 50 and 60. It is the sixth most common cancer in women worldwide (fourteenth most common cancer overall), with 320,000 new cases diagnosed in 2012, and it is the 13th most common cause of death from cancer with nearly 86,000 deaths worldwide. Endometrial cancer occurs when cells of the endometrium undergo a transformation and begin to grow and multiply wit.

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