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Entry inhibitors in HIV therapy

Author: Jacqueline D Reeves; Cynthia A Derdeyn
Publisher: Basel ; Boston : Birkhäuser Verlag, ©2007.
Series: Milestones in drug therapy.
Edition/Format:   Print book : Document   Computer File : EnglishView all editions and formats
Summary:

Entry Inhibitors in HIV Therapy details the current status of this relatively new and very dynamic class of inhibitors. The book presents a unique collection of contributors from basic research,  Read more...

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Material Type: Document
Document Type: Book, Computer File
All Authors / Contributors: Jacqueline D Reeves; Cynthia A Derdeyn
ISBN: 9783764377823 3764377828 9783764377830 3764377836
OCLC Number: 148732322
Description: ix, 200 pages : illustrations.
Contents: Introduction to entry inhibitors in the management of HIV infection.- The challenge of HIV sequence diversity in the envelope glycoproteins.- Attachment of human immunodeficiency virus to cells and its inhibition.- Inhibitors that target gp120-CD4 interactions.- Inhibitors that target gp120 interactions with coreceptor.- Inhibitors that target fusion.- Entry inhibitors as microbicides.- Entry inhibition of HIV-1 subtype C isolates.- The utility of coreceptor typing in the clinic.- Future clinical prospects for entry inhibitors.- Enfuvirtide: from basic science to FDA approval.- Targets for drug development - past and present.
Series Title: Milestones in drug therapy.
Responsibility: edited by Jacqueline D. Reeves and Cynthia A. Derdeyn.

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