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Environmental epigenomics in health and disease : epigenetics and disease origins

Autor: Randy L Jirtle; Frederick L Tyson
Editora: Berlin ; New York : Springer, ©2013.
Séries: Epigenetics and human health.
Edição/Formato   e-book : Documento : InglêsVer todas as edições e formatos
Base de Dados:WorldCat
Resumo:
Exposure to environmental toxicants is associated with changes in DNA methylation and gene expression profiles that together can contribute to increased disease susceptibility. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates, cocaine, radiation, tobacco smoke, and  Ler mais...
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Gênero/Forma: Electronic books
Formato Físico Adicional: Print version:
Environmental epigenomics in health and disease.
Berlin ; London : Springer, 2012
(OCoLC)757932132
Tipo de Material: Documento, Recurso Internet
Tipo de Documento: Recurso Internet, Arquivo de Computador
Todos os Autores / Contribuintes: Randy L Jirtle; Frederick L Tyson
ISBN: 9783642233807 3642233805
Número OCLC: 844034294
Notas: Includes index.
Descrição: 1 online resource : ill. (some col.).
Conteúdos: Fetal Origins of Adult Disease Susceptibility --
Epigenetics: How Genes and Environment Interact / Randy L. Jirtle --
Developmental Epigenomics and Metabolic Disease / Peter D. Gluckman, Felicia M. Low, Mark A. Hanson --
Sculpting Our Future: Environmental Nudging of the Imprintome / Susan K. Murphy, Cathrine Hoyo --
Epigenetics and Environmental Exposures --
Complex Phenotypes: Epigenetic Manifestation of Environmental Exposures / Christopher Faulk, Dana C. Dolinoy --
Epigenetic Effects of Ionizing Radiation / Olga Kovalchuk --
The Intersection of Genetics and Epigenetics: Reactivation of Mammalian LINE-1 Retrotransposons by Environmental Injury / Kenneth S. Ramos ... [et al.] --
Epigenetics, Gene Regulation, and Stem Cells --
Environmental Impact on Epigenetic Histone Language / John M. Denu --
Chromatin Structure and Gene Expression: Function Follows Form / Aleksandra B. Adomas, Paul A. Wade --
Epigenetics of Pluripotency / R. David Hawkins, Bing Ren --
Epigenetic Transgenerational Inheritance --
Transgenerational Epigenetic Inheritance in Drosophila / Luan Wang, Xiangyi Lu, Douglas M. Ruden --
Environmental Epigenetics and Epigenetic Transgenerational Inheritance / Michael K. Skinner --
The Nature of Human Transgenerational Responses / Marcus E. Pembrey, Lars O. Bygren, Jean Golding.
Título da Série: Epigenetics and human health.
Responsabilidade: Randy Jirtle, Frederick L. Tyson, editors.
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Resumo:

This book shows how environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity,  Ler mais...

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schema:description"Exposure to environmental toxicants is associated with changes in DNA methylation and gene expression profiles that together can contribute to increased disease susceptibility. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates, cocaine, radiation, tobacco smoke, and xenoestrogens. Particular emphasis is placed on the consequences of environmental exposures during development on epigenetic reprogramming that influences adult disease pathogenesis. Health outcomes associated with these exposures include autoimmune disorders, neurodevelopmental disorders, and cancer. Importantly, dietary supplements and drugs can modify the epigenetic effects induced by these agents, thereby reducing their toxicological impact. The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, is to give readers an overview of how environmental exposures during early development can influence disease formation by disrupting epigenetic processes and developmental programming."
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